CAJ | 학술논문

目的探讨脊神经前根小束对SD大鼠膀胱和勃起功能的选择性支配机制.方法成年雄性SD大鼠40只,10只行逆行神经示踪,30只行电生理研究:分别刺激大鼠排尿及勃起反射中枢所在脊髓节段的脊神经前根神经小束,同时记录膀胱内压、尿道灌注压和阴茎海绵体内压的变化.结果 SD大鼠排尿和勃起功能的低级中枢主要位于L6、S1脊髓节段,电刺激L6、S1脊神经前根某些小束分别引起膀胱内压、尿道灌注压和阴茎海绵体内压的改变.结论 SD大鼠L6、S1脊神经前根小束对膀胱逼尿肌、尿道外括约肌和阴茎海绵体的支配效能不同,通过显微解剖及电刺激可以区别.
목적 탐토척신경전근소속대SD대서방광화발기공능적선택성지배궤제.방법 성년웅성SD대서40지,10지행역행신경시종,30지행전생리연구:분별자격대서배뇨급발기반사중추소재척수절단적척신경전근신경소속,동시기록방광내압、뇨도관주압화음경해면체내압적변화.결과 SD대서배뇨화발기공능적저급중추주요위우L6、S1척수절단,전자격L6、S1척신경전근모사소속분별인기방광내압、뇨도관주압화음경해면체내압적개변.결론 SD대서L6、S1척신경전근소속대방광핍뇨기、뇨도외괄약기화음경해면체적지배효능불동,통과현미해부급전자격가이구별.
Objective To investigate the selective innervation of sacral anterior rootlets to micturition and erection function in SD rats. Methods Forty male SD rats of clean grade, aged 6 weeks old, were selected. Ten rats received a retrograde nerve tract tracing study. Thirty rats were chosen for an electro-physiological study. The L6, S1 spinal cord segment anterior rootlets of anesthetic rats were electrostimulated respectively. The intravesical pressure, urethral perfusion pressure and intracarvernerous pressure were recorded simultaneously and innervation effectiveness was analyzed. Results CB-HRP labeled neurons were observed mainly in L6 and S1 spinal cords. When some anterior rootlets of L6 and S1were electrostimulated, the intravesical pressure rose gradually, but the urethral perfusion pressure and the intracavernous pressure curve changed slightly; when other rootlets of the same anterior root were stimulated,the urethral perfusion pressure could reach the peak; while others were stimulated, the intracavernours pressure rose quickly, but there were no great changes in intravesical pressure and urethral perfusion pressure. Some other rootlets might lead to the simultaneous changes of 2 or 3 above-mentioned pressures.Conclusion The innervations of L6 and S1 anterior rootlets to rats' bladder detrusor, external urethral sphincter and penile cavernous body are significantly distinct. Different rootlets may be distinguished by microanatomy and electrostimulation.