CAJ | 학술논문

目的了解长沙市中老年人群(35 ～ 80岁)代谢综合征(metabolic syndrome,MS)的患病率及其流行病学特点,探讨其危险因素和防治对策.方法 2008年10月至12月在本院行健康体检的本地中老年市民,采用整群随机抽样选取800人,进行问卷、体格、常规血生化,分析MS的分布特点及危险因素.结果长沙市中老年人群MS粗患病率为24.3％,其中男性27.9％,女性19.3％,男性显著高于女性(P＜0.01).按2000年长沙市人口普查结果进行年龄构成比标化后,MS的患病率为24.4％,其中男性27.8％,女性21.9％(P＜0.01)；各代谢异常及MS的患病率存在性别及年龄差异；194例诊断MS的患者中,除必备组分中心性肥胖外,具有2种代谢异常的80例,占MS患者的41.2％,其中以血压升高+糖代谢异常最多见；具有3种代谢异常的78例,占MS患者的40.2％,其中以高TG血症+血压升高+糖代谢异常最多见；具有4种代谢异常的36例,占MS患者的18.6％；增龄、男性、超重和(或)肥胖、高LDL-C血症、高尿酸血症、糖尿病家族史等是长沙市中老年人群MS的危险因素.结论长沙市中老年人群MS患病率及各代谢异常患病率已达较高水平.随着经济发展和人口老龄化加剧,其患病率可能进一步升高,应加强MS的早期诊断及综合防治.
목적 료해장사시중노년인군(35 ～ 80세)대사종합정(metabolic syndrome,MS)적환병솔급기류행병학특점,탐토기위험인소화방치대책.방법 2008년10월지12월재본원행건강체검적본지중노년시민,채용정군수궤추양선취800인,진행문권、체격、상규혈생화,분석MS적분포특점급위험인소.결과 장사시중노년인군MS조환병솔위24.3％,기중남성27.9％,녀성19.3％,남성현저고우녀성(P＜0.01).안2000년장사시인구보사결과진행년령구성비표화후,MS적환병솔위24.4％,기중남성27.8％,녀성21.9％(P＜0.01)；각대사이상급MS적환병솔존재성별급년령차이；194례진단MS적환자중,제필비조분중심성비반외,구유2충대사이상적80례,점MS환자적41.2％,기중이혈압승고+당대사이상최다견；구유3충대사이상적78례,점MS환자적40.2％,기중이고TG혈증+혈압승고+당대사이상최다견；구유4충대사이상적36례,점MS환자적18.6％；증령、남성、초중화(혹)비반、고LDL-C혈증、고뇨산혈증、당뇨병가족사등시장사시중노년인군MS적위험인소.결론 장사시중노년인군MS환병솔급각대사이상환병솔이체교고수평.수착경제발전화인구노령화가극,기환병솔가능진일보승고,응가강MS적조기진단급종합방치.
Objective To assess the prevalence of metabolic syndrome (MS) and explore the associated risk factors with MS among 35 ～ 80 years elderly people in Changsha.Methods The survey used by cluster random sampling method (from October to December,2008 ) was carried out by the Physical Examination Center of the Second Xiangya Hospital,Changsha.All subjects aged from 35 to 80 years old had the questionnaires,physical examination,and biochemical measurements.MS was defined by IDF 2005.Results The prevalence of MS was 24.3％ among elderly people in Changsha.The prevalence of MS in male and female was 27.9％ and 19.3％,respectively; which in male was significantly higher than in females ( P ＜0.01).According to census of 2000 in Changsha,the age-adjusted rate of MS was 24.4％ among elderly people,27.8％ in male and 21.9％ in female,respectively.The metabolic abnormalities and the prevalence rate of MS were different in gender and age.Except the essential component of the central obesity in the 194 cases of MS patients,there are 80 cases include other two kinds of metabolic abnormalities,accounting for 41.2％,most of them with elevated blood pressure + sugar metabolism disorders; the most common three kinds of metabolic abnormalities of the 78 cases,accounting for 40.2％ of the people with MS,most of them with high TG + elevated blood pressure + sugar metabolism disorders; With 4 kinds of metabolic abnormalities of 36 patients,accounting for 18.6％ of the MS patients.Increasing age,male,overweight and (or) obesity,high LDL-C hematic disease,high uric acid hematic disease,diabetes were all the risk factors of the elderly people in Changsha city.Conclusions Elderly people in Changsha have a relatively high prevalence of MS,especially for male.The prevalence of MS is considerably high in Changsha,which may continue to rising with the social economic development and population aging.There is an urgent need to take actions to reduce the burden of MS.