中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2012年
5期
543-548
,共6页
近视%飞秒激光%高阶像差%LASIK
近視%飛秒激光%高階像差%LASIK
근시%비초격광%고계상차%LASIK
Myopia%Femtosecond laser%Higher-order aberrations%LASIK
目的 应用飞秒激光和微型角膜板层刀对中高度近视散光患者行LASIK手术,对比研究术后高阶像差的特征性变化.方法 前瞻性研究.中高度近视散光患者103例,其中54例行飞秒激光制瓣准分子激光角膜原位磨镶术(FS-LASIK)手术,49例行前弹力层下准分子激光角膜原位磨镶术(SBK)手术作为对照组.分别于手术前和术后1个月、3个月测量全眼波阵面像差.应用配对t检验和独立样本t检验分析FS-LASIK组术后高阶像差的变化及与SBK组术后的比较.结果 两组术后1个月和3个月时总高阶及其它高阶像差均较手术前明显增加,尤其以球样像差(C40、C60)和彗样像差(C3-1、C31)变化明显,且FS-LASIK组较对照组增加量较少.其中FS-LASIK组变化量分别为(3.4、3.7倍),(16、15倍),(0.4、1倍),(10.8、14.8倍);SBK组分别为(2.5、2.7倍),(25.5、26.5倍),(1.8、1倍),(8.4、14.7倍)(P均<0.05).但随着时间的变化,两组间的差异没有统计学意义(P均>0.05).结论 飞秒激光制瓣LASIK能有效矫正近视及散光,同时也诱导术后高阶像差的增加,但与传统机械刀制瓣LASIK相比增加量较少,对患者术后视觉质量的影响较小.随着时间的变化,这种差异变得不明显.
目的 應用飛秒激光和微型角膜闆層刀對中高度近視散光患者行LASIK手術,對比研究術後高階像差的特徵性變化.方法 前瞻性研究.中高度近視散光患者103例,其中54例行飛秒激光製瓣準分子激光角膜原位磨鑲術(FS-LASIK)手術,49例行前彈力層下準分子激光角膜原位磨鑲術(SBK)手術作為對照組.分彆于手術前和術後1箇月、3箇月測量全眼波陣麵像差.應用配對t檢驗和獨立樣本t檢驗分析FS-LASIK組術後高階像差的變化及與SBK組術後的比較.結果 兩組術後1箇月和3箇月時總高階及其它高階像差均較手術前明顯增加,尤其以毬樣像差(C40、C60)和彗樣像差(C3-1、C31)變化明顯,且FS-LASIK組較對照組增加量較少.其中FS-LASIK組變化量分彆為(3.4、3.7倍),(16、15倍),(0.4、1倍),(10.8、14.8倍);SBK組分彆為(2.5、2.7倍),(25.5、26.5倍),(1.8、1倍),(8.4、14.7倍)(P均<0.05).但隨著時間的變化,兩組間的差異沒有統計學意義(P均>0.05).結論 飛秒激光製瓣LASIK能有效矯正近視及散光,同時也誘導術後高階像差的增加,但與傳統機械刀製瓣LASIK相比增加量較少,對患者術後視覺質量的影響較小.隨著時間的變化,這種差異變得不明顯.
목적 응용비초격광화미형각막판층도대중고도근시산광환자행LASIK수술,대비연구술후고계상차적특정성변화.방법 전첨성연구.중고도근시산광환자103례,기중54례행비초격광제판준분자격광각막원위마양술(FS-LASIK)수술,49례행전탄력층하준분자격광각막원위마양술(SBK)수술작위대조조.분별우수술전화술후1개월、3개월측량전안파진면상차.응용배대t검험화독립양본t검험분석FS-LASIK조술후고계상차적변화급여SBK조술후적비교.결과 량조술후1개월화3개월시총고계급기타고계상차균교수술전명현증가,우기이구양상차(C40、C60)화혜양상차(C3-1、C31)변화명현,차FS-LASIK조교대조조증가량교소.기중FS-LASIK조변화량분별위(3.4、3.7배),(16、15배),(0.4、1배),(10.8、14.8배);SBK조분별위(2.5、2.7배),(25.5、26.5배),(1.8、1배),(8.4、14.7배)(P균<0.05).단수착시간적변화,량조간적차이몰유통계학의의(P균>0.05).결론 비초격광제판LASIK능유효교정근시급산광,동시야유도술후고계상차적증가,단여전통궤계도제판LASIK상비증가량교소,대환자술후시각질량적영향교소.수착시간적변화,저충차이변득불명현.
Objective To compare the changes of higher-order aberrations of patients with high degree of myopia pre- and post- LASIK with femtosecond laser and mechanical microkeratome.Methods In this prospective study,103 patients were included.A trial group had 54 patients with the FS-LASIK,and 49 cases with SBK as the control group.Ocular higher-order aberrations were measured at pre-operation,1 month and 3 months post-operation.The paired t test and the independent t test were used to analyze the changes of aberrations after FS-LASIK and SBK,and compared the difference between the two groups. Results At the 1st and 3rd month post-operation,it had shown an increase in all higher-order aberrations both in two groups,especially for the spherical-like aberrations (C40,C60) and the coma-like aberrations (C3-1,C31).In FS-LASIK group,they were increased (3.4,3.7 times),(16,15 times),(0.4,1 times),(10.8,14.8 times); while in SBK group were (2.5,2,7 times),(25.5,26.5 times),(1.8,1 times),(8.4,14.7times) (P <0.05),respectively.The change of higher-order aberrations in FS-LASIK group was loss than the control group.However,as the change of time,the difference between the two groups was not statistically significant (P >0.05).Conclusions LASIK with the femtosecond laser can effectively correct myopia and astigmatism,it also can induce some higher-order aberrations but superior than the control group.However,as the change of time,the difference between the two groups is not significant.