中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2010年
7期
22-23
,共2页
慢性重型肝炎%胰岛素生长因子-1
慢性重型肝炎%胰島素生長因子-1
만성중형간염%이도소생장인자-1
Chronic severe hepatitis%Insulin-like growth factor-1
目的 探讨慢性重型肝炎患者胰岛素生长因子-1(IGF-1)的变化与病情的关系.方法 用化学发光法检测31例慢性重型肝炎患者IGF-1的动态变化,并比较生存患者和死亡患者的IGF-1变化.结果 慢性重型肝炎患者IGF-1变化与凝血酶原活动度(PTA)的变化相一致.生存患者IGF-1在达到一个最低值后随着PTA的增高而增高;死亡患者的IGF-1则进行性降低,在死亡前达极低值.生存患者与死亡患者IGF-1、TBiL、PTA差异有统计学意义.结论 慢性重型肝炎患者IGF-1明显降低,而且与PTA的变化有相关性,动态观察慢性重型肝炎患者IGF-1的变化可作为判断病情的指标之一.
目的 探討慢性重型肝炎患者胰島素生長因子-1(IGF-1)的變化與病情的關繫.方法 用化學髮光法檢測31例慢性重型肝炎患者IGF-1的動態變化,併比較生存患者和死亡患者的IGF-1變化.結果 慢性重型肝炎患者IGF-1變化與凝血酶原活動度(PTA)的變化相一緻.生存患者IGF-1在達到一箇最低值後隨著PTA的增高而增高;死亡患者的IGF-1則進行性降低,在死亡前達極低值.生存患者與死亡患者IGF-1、TBiL、PTA差異有統計學意義.結論 慢性重型肝炎患者IGF-1明顯降低,而且與PTA的變化有相關性,動態觀察慢性重型肝炎患者IGF-1的變化可作為判斷病情的指標之一.
목적 탐토만성중형간염환자이도소생장인자-1(IGF-1)적변화여병정적관계.방법 용화학발광법검측31례만성중형간염환자IGF-1적동태변화,병비교생존환자화사망환자적IGF-1변화.결과 만성중형간염환자IGF-1변화여응혈매원활동도(PTA)적변화상일치.생존환자IGF-1재체도일개최저치후수착PTA적증고이증고;사망환자적IGF-1칙진행성강저,재사망전체겁저치.생존환자여사망환자IGF-1、TBiL、PTA차이유통계학의의.결론 만성중형간염환자IGF-1명현강저,이차여PTA적변화유상관성,동태관찰만성중형간염환자IGF-1적변화가작위판단병정적지표지일.
Objective To study the relationship between the IGF-1 changes of chronic severe hepatitis and the development of disease.Methods Using Chemiluminescence method detects the IGF-1 dynamic variety of 31 cases of chronic severe hepatitis.The IGF-1 of survival cases and dead cases were compared.Results The varieties of IGF-1 of chronic severe hepatitis cases were consistent with the varieties of PTA.After the IGF-1 of survival cases arrived at the lowest degree,the increasing degree of IGF-1 was couple with the variety of PTA.But the IGF-1 of dead cases were consecutively decreasing and arriving at the lowest degree before death.There was significant variabihty in IGF-1,Tbil and PTA between the survival cases and the dead cases.Conclusion The IGF-1 of chronic severe hepatitis show marked decreasing and relating with the variety of PTA.The dynamic observation of IGF-1 can be one of the indicators on disease development.
