CAJ | 학술논문

目的探讨卒中后抑郁(post-stroke depression,PSD)患者静息态脑功能磁共振成像(functional magnetic resonance imaging,fMRI)特征.方法分别对13例PSD患者以及无PSD卒中患者进行静息态fMRI扫描,采用局部一致性(regional homogeneity,ReHo)作为指标,分析PSD患者脑功能.结果与对照组相比,PSD组患者左侧额中回、右侧额上回、右侧额中回、右侧扣带前回、右侧扣带后回、左侧岛叶、左侧尾状核和左侧海马的ReHo值显著降低.结论 PSD患者存在静息态神经环路功能异常,提示在临床治疗过程中需要重视卒中患者的情绪状态.
목적 탐토졸중후억욱(post-stroke depression,PSD)환자정식태뇌공능자공진성상(functional magnetic resonance imaging,fMRI)특정.방법 분별대13례PSD환자이급무PSD졸중환자진행정식태fMRI소묘,채용국부일치성(regional homogeneity,ReHo)작위지표,분석PSD환자뇌공능.결과 여대조조상비,PSD조환자좌측액중회、우측액상회、우측액중회、우측구대전회、우측구대후회、좌측도협、좌측미상핵화좌측해마적ReHo치현저강저.결론 PSD환자존재정식태신경배로공능이상,제시재림상치료과정중수요중시졸중환자적정서상태.
Objective To investigate the characteristics of resting-state functional magnetic resonance imaging (fMRI)in patients post-stroke depression (PSD).Methods Resting-state fMRI scans were performed in 13 patients with and without post-stroke depression.A regional homogeneity (ReHo) approach was used as an indicator.The brain function was analyzed in patients with post-stroke depression.Results Compared to a control group,the ReHo values decreased significantly in a PSD group in the left middle frontal gyrus,right superior frontal gyrus,right middle frontal gyrus,right anterior cingulate gyrus,right posterior cingutate gyrus,left insular lobe,left caudate nucleus,and left hippocampus.Conclusions The patients with PSD had restingstate neural circuit dysfunction,suggesting that the need to focus on the emotional state of stroke patients in the clinical treatment process.