中国科学院研究生院学报
中國科學院研究生院學報
중국과학원연구생원학보
JOURNAL OF THE GRADUATE SCHOOL OF THE CHINESE ACADEMY OF SCIENCES
2012年
4期
571-575
,共5页
富电性底物%缺电子催化剂%不对称氢化%机理
富電性底物%缺電子催化劑%不對稱氫化%機理
부전성저물%결전자최화제%불대칭경화%궤리
electron-rich substrates%electron-deficient Rh-BINAP catalyst%asymmetric hydrogenation%mechanism
合成了4种富电性的脱氢α-氨基酸衍生物,将缺电子催化剂Rh-3,5-CF3- (R) -BINAP用于这几种底物的不对称氢化反应中.讨论了底物上取代基及空间位阻对对映选择性的影响.
閤成瞭4種富電性的脫氫α-氨基痠衍生物,將缺電子催化劑Rh-3,5-CF3- (R) -BINAP用于這幾種底物的不對稱氫化反應中.討論瞭底物上取代基及空間位阻對對映選擇性的影響.
합성료4충부전성적탈경α-안기산연생물,장결전자최화제Rh-3,5-CF3- (R) -BINAP용우저궤충저물적불대칭경화반응중.토론료저물상취대기급공간위조대대영선택성적영향.
Four electron-rich α-acetamidocinnamic acid derivatives were prepared and used as substrates in the asymmetric hydrogenation catalyzed by electron-deficient Rh-3,5-CF3-(R)-BINAP.Influence of the electronic properties of substituted groups in the substrates and their steric hindrance on the enantioselectivity of the product were discussed.
