CAJ | 학술논문

近年来,纳米材料药物因其独特的生物学特性而被广泛应用于医疗领域,但其安全性问题已成为广大学者所关注的焦点。基因组学和蛋白组学的快速发展,为研究纳米药物对机体的毒性作用机理提供了相关的技术支持。本文介绍了基因组学和蛋白组学的概念及其核心技术、纳米药物毒性,并对基因组学和蛋白组学在纳米药物毒性研究中的应用进行了综述。
근년래,납미재료약물인기독특적생물학특성이피엄범응용우의료영역,단기안전성문제이성위엄대학자소관주적초점。기인조학화단백조학적쾌속발전,위연구납미약물대궤체적독성작용궤리제공료상관적기술지지。본문개소료기인조학화단백조학적개념급기핵심기술、납미약물독성,병대기인조학화단백조학재납미약물독성연구중적응용진행료종술。
In recent years,nanometer material drugs are widely used in the medical field because of its unique biological characters,but its secure issues have been concerned by the broad scholars.The rapid development of genomics and proteomics provided the technical support for the toxic mechanism research of the nano drug.This paper introduced the concepts and the core technologies of genomics and proteomics,the toxicity of nano drug,and summarized the application of genomics and proteomics in toxicity research of nano drug。