CAJ | 학술논문

　　目的分析我中心2007年与2012年抗抑郁药应用情况，了解抗抑郁药应用趋势，为临床合理用药提供参考。方法对我中心2007和2012年抑郁症和精神科住院患者人数、精神科药品总销售金额、抗抑郁药的应用品种、销售金额、用药频度等情况进行对比统计和分析。结果我中心2012年与2007年比较，抑郁症住院人数增长率为115.85%，抗抑郁药销售额涨幅为25.39%，选择性5-HT再摄取抑制剂( SSRIs )是目前临床应用最多的新型抗抑郁药，三环类抗抑郁药( TCAs )用量明显下降。结论抑郁症就诊率以及抗抑郁药用量有上升趋势，SSRIs类抗抑郁药在临床治疗中有举足轻重的作用。同时新型5-HT与NE再摄取抑制剂( SNRIs )有良好的应用前景。
　　목적분석아중심2007년여2012년항억욱약응용정황，료해항억욱약응용추세，위림상합리용약제공삼고。방법대아중심2007화2012년억욱증화정신과주원환자인수、정신과약품총소수금액、항억욱약적응용품충、소수금액、용약빈도등정황진행대비통계화분석。결과아중심2012년여2007년비교，억욱증주원인수증장솔위115.85%，항억욱약소수액창폭위25.39%，선택성5-HT재섭취억제제( SSRIs )시목전림상응용최다적신형항억욱약，삼배류항억욱약( TCAs )용량명현하강。결론억욱증취진솔이급항억욱약용량유상승추세，SSRIs류항억욱약재림상치료중유거족경중적작용。동시신형5-HT여NE재섭취억제제( SNRIs )유량호적응용전경。
Objective To provide reference for clinical rational use by analyzing the antidepressant use situation between in 2007 and in 2012 at our center and by studying the tendency of the antidepressants application .Methods Contrast statistics and analysis was conducted in terms of in-patient numbers at depression and psychiatry department at our center between in 2007 and in 2012,the total psychiatry drug sales amount,the application variety,sales amount,and frequency of drug use of antidepressants.Results Compared with 2007,in 2012 the grow th rate of in-patient number of depression sufferers was 115 .85 % ,the antidepressant sales amount increase was 25 .39 % ,selective 5-HTSSR Is was the most popular new antidepressant,while the use of TCAs decreased significantly.Conclusion The outpatient rate of depression and the use of antidepressant take on a rising trend .SSR Is plays a key role in clinical treatm ent of depression and the new 5-HTSNR Is has good application prospect.