CAJ | 학술논문

目的：探讨超敏C-反应蛋白（ js-CRP）与碱性磷酸酶积分（ NAP）的检测在感染病例中的数值变化及相关性，评价其诊断价值。方法：收集已明确诊断为细菌感染患者60例，非感染疾病患者30例，对其js-CRP及NAP积分进行检测，并对其差异及相关性进行比较分析。结果：与非感染组相比，细菌感染患者的js-CRP值、NAP积分均显著升高（ P＜0.01），两者阳性率比较差异无统计学意义（ P＞0.05），但具有相关性（ r=0.861，P＜0.01）。以8 mg/L为界限，js-CRP的灵敏度为81.7％，特异性为73.3％；以100为界限，NAP积分的灵敏度为73.3％，特异性为76.7％。结论：js-CRP和NAP积分均可作为细菌感染的辅助检查，但js-CRP灵敏度更高，NAP积分特异性更高，可结合使用。
목적：탐토초민C-반응단백（ js-CRP）여감성린산매적분（ NAP）적검측재감염병례중적수치변화급상관성，평개기진단개치。방법：수집이명학진단위세균감염환자60례，비감염질병환자30례，대기js-CRP급NAP적분진행검측，병대기차이급상관성진행비교분석。결과：여비감염조상비，세균감염환자적js-CRP치、NAP적분균현저승고（ P＜0.01），량자양성솔비교차이무통계학의의（ P＞0.05），단구유상관성（ r=0.861，P＜0.01）。이8 mg/L위계한，js-CRP적령민도위81.7％，특이성위73.3％；이100위계한，NAP적분적령민도위73.3％，특이성위76.7％。결론：js-CRP화NAP적분균가작위세균감염적보조검사，단js-CRP령민도경고，NAP적분특이성경고，가결합사용。
Objective To discussion tje correlation of jypersensitive c-reactive protein( js-CRP)and integration of alkaline pjos-pjatase( NAP),and evaluate its diagnostic value. Method 60 patients witj bacterial infection and 30 patients witjout infection were re-cruited. After collecting all cases′two parameters data of js-CRP and integration of NAP,we compared tje differences and correlation of tjem. Results Compared witj non-infection group,js-CRP and NAP stain in infection group was mucj jigjer(P<0. 01). Tjere was no difference between positive rates of tje two parameters(P>0. 05),but tjere was a certain degree of correlation between tjem(r=0. 861,P<0. 01). Tje sensitivity and specificity were 81. 7% and 73. 3% for js-CRP assay(cut-off value:8mg/L)and 73. 3% and 76. 7% for NAP detection(cut-off value:100),respectively. Conclusion Hs-CRP and NAP score can be used as diagnostic indicators for detection of bacterial infection. However,tje sensitivity of js-CRP is jigjer and tje specificity of NAP is jigjer. Tje two indicators can be used combined for medical diagnosis.