CAJ | 학술논문

采用试管稀释法和纸片法测定9株乳房链球菌对克林霉素的耐药性，通过PCR反应检测克林霉素的耐药性基因，并进行测序比较。发现克林霉素对乳房链球菌的抗菌活力较强，克林霉素耐药基因同时存在于乳房链球菌的染色体和质粒上。
채용시관희석법화지편법측정9주유방련구균대극림매소적내약성，통과PCR반응검측극림매소적내약성기인，병진행측서비교。발현극림매소대유방련구균적항균활력교강，극림매소내약기인동시존재우유방련구균적염색체화질립상。
A total 9 isolates of the Streptococcus uberis were tested for minimal inhibitory concentration (MIC)and antibiotic susceptibility to clindamycin by using test-tube dilution and disc diffusion methods.PCR was used to detect the erm gene in Streptococcus uberis.We find that clindamycin has strong antibacterial activities.Comparision of erm (S.uberis)and ermS(S.sanguis)sequences showed 99%(750/757)conservation,which also suggests erm gene located on both plasmid and chromosome.