现代诊断与治疗
現代診斷與治療
현대진단여치료
MODERN DIAGNOSIS AND TREATMENT
2001年
2期
75-77
,共3页
张育苗%王永明%王招定%黄卫宇%金志刚
張育苗%王永明%王招定%黃衛宇%金誌剛
장육묘%왕영명%왕초정%황위우%금지강
呼吸系统感染%血清心肌磷酸激酶%血清心肌肌钙蛋白Ⅰ
呼吸繫統感染%血清心肌燐痠激酶%血清心肌肌鈣蛋白Ⅰ
호흡계통감염%혈청심기린산격매%혈청심기기개단백Ⅰ
目的 探讨急性呼吸系统感染患儿血清CK-MB增高而无心肌炎临床症状和心电图改变的原因。方法 对急性呼吸系感染患儿于病程的1~5天内采静脉血同时测定CK-MB(采用免疫抑制法)和CTnⅠ(采用夹心ELISA法),并动态观察病人临床症状、心电图改变以判断是否合并心肌炎。结果 130例急性呼吸系感染患儿中血清CK-MB增高58例,血清CTnⅠ增高3例,其阳性率为100%,经卡方检验P<0.05,差异有显著性。127例临床无心肌炎的病例中,血清CK-MB增高55例,正常72例,127例患儿中血清CK-MB增高组、CK-MB正常组与正常儿童对照组三组间CTnⅠ值经方差分析P>0.05,差异无显著性。结论 应用免疫法测定的血清CK-MB值不能作为判断呼吸系感染时有无心肌损伤的“金指标”,应改用质量法测定血清CK-MB,或测定血清CTnⅠ来补充。
目的 探討急性呼吸繫統感染患兒血清CK-MB增高而無心肌炎臨床癥狀和心電圖改變的原因。方法 對急性呼吸繫感染患兒于病程的1~5天內採靜脈血同時測定CK-MB(採用免疫抑製法)和CTnⅠ(採用夾心ELISA法),併動態觀察病人臨床癥狀、心電圖改變以判斷是否閤併心肌炎。結果 130例急性呼吸繫感染患兒中血清CK-MB增高58例,血清CTnⅠ增高3例,其暘性率為100%,經卡方檢驗P<0.05,差異有顯著性。127例臨床無心肌炎的病例中,血清CK-MB增高55例,正常72例,127例患兒中血清CK-MB增高組、CK-MB正常組與正常兒童對照組三組間CTnⅠ值經方差分析P>0.05,差異無顯著性。結論 應用免疫法測定的血清CK-MB值不能作為判斷呼吸繫感染時有無心肌損傷的“金指標”,應改用質量法測定血清CK-MB,或測定血清CTnⅠ來補充。
목적 탐토급성호흡계통감염환인혈청CK-MB증고이무심기염림상증상화심전도개변적원인。방법 대급성호흡계감염환인우병정적1~5천내채정맥혈동시측정CK-MB(채용면역억제법)화CTnⅠ(채용협심ELISA법),병동태관찰병인림상증상、심전도개변이판단시부합병심기염。결과 130례급성호흡계감염환인중혈청CK-MB증고58례,혈청CTnⅠ증고3례,기양성솔위100%,경잡방검험P<0.05,차이유현저성。127례림상무심기염적병례중,혈청CK-MB증고55례,정상72례,127례환인중혈청CK-MB증고조、CK-MB정상조여정상인동대조조삼조간CTnⅠ치경방차분석P>0.05,차이무현저성。결론 응용면역법측정적혈청CK-MB치불능작위판단호흡계감염시유무심기손상적“금지표”,응개용질량법측정혈청CK-MB,혹측정혈청CTnⅠ래보충。
Objective To study the cause of elevation of CK-MB in infants with withont acute respiratory system infection no symptoms of cardititis and abnormal ECG.Method CK-MB and CTnⅠ were examined in the patients suffering from acute respiratory system infection within 1 tos days.Meanwhile,the clinical symptoms and ECG were dynamically observed in order to conclude whether they were associated with myocarditis.Results 130 cases were studied in which CK-MB elevated in 58 cases,CTnⅠ elevated in 3 cases,3 cases could be made definite diagnoses of myocardititis.The elevation of CTnⅠ was used to prediagnose the positive rate of myocarditis,up to 100 percent(P<0.05).In 127 cases without myocarditis,CK-MB elevated in 55 cases,and was normal in 72 cases.Conclusions CK-MB examined by immunization is not a gold standard of cadiomyocyte injury during acute respiratory system infection.