CAJ | 학술논문

目的通过多导睡眠图(PSG)及临床指标预测阻塞型睡眠呼吸暂停综合征患者(OSAS)的经鼻持续气道正压通气(nCPAP)最佳压力(Pmin)。方法采用RHK-5500型多导睡眠呼吸监测系统连接BiPAP系统测22例OSAS患者nCPAP的Pmin，推导其与呼吸紊乱指数(RDI)、体重指数(BMI)及颈围(NECK)等指标的回归方程，用回归方程预测的Pmin治疗20例OSAS患者，同时多导睡眠图监测治疗效果。结果 RDI、LSaQ2指标与Pmin呈直线正相关。结论临床上可根据患者的RDI、LSaO2预测nCPAP治疗的最佳压力。
목적통과다도수면도(PSG)급림상지표예측조새형수면호흡잠정종합정환자(OSAS)적경비지속기도정압통기(nCPAP)최가압력(Pmin)。방법채용RHK-5500형다도수면호흡감측계통련접BiPAP계통측22례OSAS환자nCPAP적Pmin，추도기여호흡문란지수(RDI)、체중지수(BMI)급경위(NECK)등지표적회귀방정，용회귀방정예측적Pmin치료20례OSAS환자，동시다도수면도감측치료효과。결과 RDI、LSaQ2지표여Pmin정직선정상관。결론림상상가근거환자적RDI、LSaO2예측nCPAP치료적최가압력。
Objective To predict an optimal level of continuous positive airway pressure (CPAP) in the management of obstructive sleep apnea syndrome (OSAS) by relating certain parameters of respiratory disturbance and sleep hypoxcmia. Methods 42 patients with OSAS were enrolled in the study. The actual levels of CPAP (Pmin) in Group one (22 patients, aged 54. 3 ± 12. 6yrs ) were determined by a RHK-5500 mode polysomnographic system plus BiPAP (S-T/D) system. The actual Pmin was related to the respiratory disturbance index (RDI). The correlation regression equations were calculated. 20 patients with OSAS (Group two, aged 50. 1 ± 11.8 yrs) were treated with the predicted nasal CPAP which was derived from the regression equation. Results There was a close postive linear correlation between RDI or LSaO2 and actual Pmin. Symptoms and polysomnographic parameters improved significantly after the CPAP treatment in these patients. The efficacy showed no significant difference between the two groups. Conclusions It was suggested that RDI is of value and simple in predicting the pressure level of CPAP in the management of OSAS with nasal CPAP.