CAJ | 학술논문

目的评价A型肉毒毒素局部注射治疗颞下颌关节紊乱病(TMD)的临床疗效。方法对11例经保守治疗无效的TMD患者，给予局部注射A型肉毒毒素150U，双侧嚼肌各50U，双侧颞肌各25U。分析治疗前后不同时期患者的最大张口度、疼痛值、口颌功能及局部压痛值的变化。结果治疗后不同时期患者最大张口度、疼痛、口颌功能及局部压痛均较治疗前有显著改善(P＜0.05)。结论 A型肉毒毒素局部注射治疗TMD，能有效改善患者的张口度，缓解疼痛。
목적평개A형육독독소국부주사치료섭하합관절문란병(TMD)적림상료효。방법대11례경보수치료무효적TMD환자，급여국부주사A형육독독소150U，쌍측작기각50U，쌍측섭기각25U。분석치료전후불동시기환자적최대장구도、동통치、구합공능급국부압통치적변화。결과치료후불동시기환자최대장구도、동통、구합공능급국부압통균교치료전유현저개선(P＜0.05)。결론 A형육독독소국부주사치료TMD，능유효개선환자적장구도，완해동통。
Objective　To evaluate the clinical efficacy of botulinum toxin A in the treatment of temporomandibular joint disorder (TMD).Methods　11 patients with TMD were treated with 150 units of botulinum toxin A.Both masseter muscles were injected with 50 units each.Similarly,both temporalis muscles received 25 units each.Clinical data including maximum mouth opening,pain,subjective function and tenderness to palpation were collected and then analyzed.Results　The maximum mouth opening,pain,subjective function and tenderness to palpation of the patients improved significantly (P＜0.05) at different period of time after injection.Conclusion　The use of botulinum toxin A for treatment of TMD is effective in reducing pain,increasing mouth opening and improving quality of life in patients with TMD.