中国煤炭工业医学杂志
中國煤炭工業醫學雜誌
중국매탄공업의학잡지
CHINESE JOURNAL OF COAL INDUSTRY MEDICINE
2000年
11期
1085-1086
,共2页
王东风%周君同%徐宁%马希明
王東風%週君同%徐寧%馬希明
왕동풍%주군동%서저%마희명
感染 幽门螺旋杆菌 IgG IgA IGM 特异抗体 脑梗死 心肌梗死 老年
感染 幽門螺鏇桿菌 IgG IgA IGM 特異抗體 腦梗死 心肌梗死 老年
감염 유문라선간균 IgG IgA IGM 특이항체 뇌경사 심기경사 노년
Infection Helicobactor pylori IgG IgA IgM Specific antibiotics Cerebral infarction My-ocardial infarction elderly
目的 通过比较脑梗死和心肌梗死患者与对照组血清幽门螺旋杆菌特异抗体IgG、IgA、IGM的阳性率，探讨幽门螺旋杆菌与脑梗死和心肌梗死的关系。方法老年脑梗死组69例，老年心肌梗死32例，对照组42例。应用酶联免疫分析法分别测定三组IgG、IgA、IGM的阳性率。结果脑梗死组幽门螺旋杆菌特异抗体IgG、IgA、IGM阳性率分别为82.6％、57.8％、19.5％，心肌梗死组为87.6％、60.2％、23.7％；对照组则分别为52.4％、28.6％、7.2％，与患病组相差有高度显著性(P<0.01)。患病组IgG和/或IgA组合以及IgG和/或IgA和/或IGM组合阳性率明显高于对照组(P<0.01)。患病组甘油三酯与 HP 特异抗体IgGIgA呈明显正相关(分别P<0.01)。结论幽门螺旋杆菌感染与脑梗死和心肌梗死的发病密切相关；可能为缺血性心脑血管疾病的又一危险因素。
目的 通過比較腦梗死和心肌梗死患者與對照組血清幽門螺鏇桿菌特異抗體IgG、IgA、IGM的暘性率，探討幽門螺鏇桿菌與腦梗死和心肌梗死的關繫。方法老年腦梗死組69例，老年心肌梗死32例，對照組42例。應用酶聯免疫分析法分彆測定三組IgG、IgA、IGM的暘性率。結果腦梗死組幽門螺鏇桿菌特異抗體IgG、IgA、IGM暘性率分彆為82.6％、57.8％、19.5％，心肌梗死組為87.6％、60.2％、23.7％；對照組則分彆為52.4％、28.6％、7.2％，與患病組相差有高度顯著性(P<0.01)。患病組IgG和/或IgA組閤以及IgG和/或IgA和/或IGM組閤暘性率明顯高于對照組(P<0.01)。患病組甘油三酯與 HP 特異抗體IgGIgA呈明顯正相關(分彆P<0.01)。結論幽門螺鏇桿菌感染與腦梗死和心肌梗死的髮病密切相關；可能為缺血性心腦血管疾病的又一危險因素。
목적 통과비교뇌경사화심기경사환자여대조조혈청유문라선간균특이항체IgG、IgA、IGM적양성솔，탐토유문라선간균여뇌경사화심기경사적관계。방법노년뇌경사조69례，노년심기경사32례，대조조42례。응용매련면역분석법분별측정삼조IgG、IgA、IGM적양성솔。결과뇌경사조유문라선간균특이항체IgG、IgA、IGM양성솔분별위82.6％、57.8％、19.5％，심기경사조위87.6％、60.2％、23.7％；대조조칙분별위52.4％、28.6％、7.2％，여환병조상차유고도현저성(P<0.01)。환병조IgG화/혹IgA조합이급IgG화/혹IgA화/혹IGM조합양성솔명현고우대조조(P<0.01)。환병조감유삼지여 HP 특이항체IgGIgA정명현정상관(분별P<0.01)。결론유문라선간균감염여뇌경사화심기경사적발병밀절상관；가능위결혈성심뇌혈관질병적우일위험인소。
Objective To find out the relations between helicobactor plyori infection and the cerebral infarction aswell as myocardial infarction, and to explore their clinical significance. Methods 69 cases of cerebral infarction and 32cases of myocardial infarction as well as 42 controls were selected for the study. Positive rates of IgG, IgA and IgM inthe above three groups were detected by enzyme linked immunosorbent assay. Results Seropositive rates of IgG, IgAand IgM were 82.6%, 57.8000 and 19. 5000 in cerebral infarction; 87. 60%00, 60. 2% and 23.7% in myocardial infarctionand 52.4%, 28.6% and 7.2% in the control group. A significant difference was shown between the study group andthe control group (P＜0.01). Trilyceride levels in both the cerebral and myocardial groups were higher than that inthe control group (P＜0. 01). There was a significant correlation between H pylori and trilyceride (P＜0.01). Con-clusion Hpylori is significantly correlated with cerebral infarction and myocardial infarction in elderly patients. H py-lori infection is probably another dangerous factor for ischemic cardiocascular and cerebrovascular diseases.
