首都医科大学学报
首都醫科大學學報
수도의과대학학보
JOURNAL OF CAPITAL UNIVERSITY OF MEDICAL SCIENCES
2001年
1期
21-23
,共3页
王蓬文%杨佩荪%周以建%陈晋杰%张连柱%董瑞安
王蓬文%楊珮蓀%週以建%陳晉傑%張連柱%董瑞安
왕봉문%양패손%주이건%진진걸%장련주%동서안
胎羊%创伤愈合%特殊染色%电镜
胎羊%創傷愈閤%特殊染色%電鏡
태양%창상유합%특수염색%전경
为促进伤口以完全再生的方式无瘢痕或较少瘢痕愈合,在实验羊背部脊椎两侧制做伤口模型,用羊水、胎皮、脐血等不同成分对伤口进行治疗,并于治疗后1、3、7、14d取材,分别做HE、马宋三色染色,7d组做电镜切片,观察疗效。结果:同期内羊水组、胎皮组及脐血组比云南白药组及生理盐水组炎症清除反应及肉芽、胶原生长好,但未发现有明显减少瘢痕愈合的作用。结果提示:胎羊不同组分(羊水、胎皮、脐血)可促进伤口愈合,缩短愈合时间。
為促進傷口以完全再生的方式無瘢痕或較少瘢痕愈閤,在實驗羊揹部脊椎兩側製做傷口模型,用羊水、胎皮、臍血等不同成分對傷口進行治療,併于治療後1、3、7、14d取材,分彆做HE、馬宋三色染色,7d組做電鏡切片,觀察療效。結果:同期內羊水組、胎皮組及臍血組比雲南白藥組及生理鹽水組炎癥清除反應及肉芽、膠原生長好,但未髮現有明顯減少瘢痕愈閤的作用。結果提示:胎羊不同組分(羊水、胎皮、臍血)可促進傷口愈閤,縮短愈閤時間。
위촉진상구이완전재생적방식무반흔혹교소반흔유합,재실험양배부척추량측제주상구모형,용양수、태피、제혈등불동성분대상구진행치료,병우치료후1、3、7、14d취재,분별주HE、마송삼색염색,7d조주전경절편,관찰료효。결과:동기내양수조、태피조급제혈조비운남백약조급생리염수조염증청제반응급육아、효원생장호,단미발현유명현감소반흔유합적작용。결과제시:태양불동조분(양수、태피、제혈)가촉진상구유합,축단유합시간。
Different constituents of fetal lamb were used to induce scarlesswound healing. Sheep wound models were prepared on both sides of vertebral column. Am niotic fluid, fetal skin and cord blood were picked up from p regnant sheep. Total protein amounts of different constituents were examined. Different constituents of fetal lamb were used to treat adult sheep wounds. To investigate the repair, compared the wound healing of 1 d, 3 d, 7 d and 14 d in the adult sheep during different treatments in HE and Masson staining. Elec tronic microscope observation was done in 7 d wounds. Results: During the same p eriod, clean inflammation reaction, granulation tissue and collagen desposition are better in amniotic fluid group, fetal skin group and cord blood group than i n Yunnan bai yao group and N.S group. But didn't find the scarless wound heal ing in those groups. Conclusion: The different constituents of fetal lamb may im p rove the wound repair in adult sheep and make wound healing in a shorter time.