中外医疗
中外醫療
중외의료
CHINA FOREIGN MEDICAL TREATMENT
2009年
19期
15-16
,共2页
林爱珍%陈朝轩%潘景良%薛红燕
林愛珍%陳朝軒%潘景良%薛紅燕
림애진%진조헌%반경량%설홍연
唐氏综合征%甲胎蛋白%绒毛膜促性腺激素%游离雌三醇
唐氏綜閤徵%甲胎蛋白%絨毛膜促性腺激素%遊離雌三醇
당씨종합정%갑태단백%융모막촉성선격소%유리자삼순
Down's syndrome%Alpha feto Protein%Total beta human chronic gonadotropin%Unconjugated estriol
目的 探讨孕妇体重,孕周对孕中期唐氏综合征(DS)产前筛查血清学指标的影响. 方法对2371例孕中期(15～22周)孕妇血清进行3项指标检测,利用统计软件Curve Expert 1.3拟合出随着不同体重,孕周3项指标中位数变化的曲线. 结果 AFP,FE3随着孕周升高,ThCG随着孕周降低, 3条曲线的相关系数r分别为0.998,0.999,0.990.AFP,ThCG随体重上升而下降,曲线的相关系数分别为0.995,0.930.FE3在体重组之间无差别,方差分析 P>0.05. 结论不同体重,孕周3项指标中位数变化的曲线,对唐氏筛查高风险的统计具有一定的影响因素.
目的 探討孕婦體重,孕週對孕中期唐氏綜閤徵(DS)產前篩查血清學指標的影響. 方法對2371例孕中期(15～22週)孕婦血清進行3項指標檢測,利用統計軟件Curve Expert 1.3擬閤齣隨著不同體重,孕週3項指標中位數變化的麯線. 結果 AFP,FE3隨著孕週升高,ThCG隨著孕週降低, 3條麯線的相關繫數r分彆為0.998,0.999,0.990.AFP,ThCG隨體重上升而下降,麯線的相關繫數分彆為0.995,0.930.FE3在體重組之間無差彆,方差分析 P>0.05. 結論不同體重,孕週3項指標中位數變化的麯線,對唐氏篩查高風險的統計具有一定的影響因素.
목적 탐토잉부체중,잉주대잉중기당씨종합정(DS)산전사사혈청학지표적영향. 방법대2371례잉중기(15～22주)잉부혈청진행3항지표검측,이용통계연건Curve Expert 1.3의합출수착불동체중,잉주3항지표중위수변화적곡선. 결과 AFP,FE3수착잉주승고,ThCG수착잉주강저, 3조곡선적상관계수r분별위0.998,0.999,0.990.AFP,ThCG수체중상승이하강,곡선적상관계수분별위0.995,0.930.FE3재체중조지간무차별,방차분석 P>0.05. 결론불동체중,잉주3항지표중위수변화적곡선,대당씨사사고풍험적통계구유일정적영향인소.
Objectives Discussion Pregnant weight, gestational age of second-trimester Down syndrome(DS)Prenatal screening serological indicators.Methods 2371 cases of second trimester (15～22weeks)maternal serum for three indicators of detection,The use of statistical software CurveExpert 1.3 fitted with a different weight, gestational age of three indicators of changes in the median curve.Results AFP,EF3 levels rise with gestational age. ThCG level goes down with gestational weeks.The coefficient of correlation is 0.998,0.999, 0.990, respectively. AFP, ThCG levels decrease as the mother body weight rises,the coefficient of correlation is 0.995,0.930.EF3 shows no difference in different weight groups.Though ANOVA,P>0.05.Conclusions Different weight, gestational age of three indicators of changes in the median curve, Screening high-risk for Down's statistics have a certain factor.
