CAJ | 학술논문

目的研究超声评分法对干燥综合征涎腺病变的诊断价值.方法由两名医师对103例腮腺和颌下腺4个腺体的声像图进行评分,进行统计分析确定诊断最佳阈值及其诊断效力.结果两名医师评分结果的Kappa值为0.80.疾病组腮腺、颌下腺评分和总评分均明显高于对照组.腮腺、颌下腺评分和总评分的ROC曲线下面积分别为0.98、0.95、0.99,总评分的最佳诊断阈值为8,诊断敏感性、特异性、阳性预测值和阴性预测值分别为93%、97%、95%、95%.结论腮腺和颌下腺4个腺体的超声评分法评价干燥综合征涎腺病变具有较高的诊断价值.
목적 연구초성평분법대간조종합정연선병변적진단개치.방법 유량명의사대103례시선화합하선4개선체적성상도진행평분,진행통계분석학정진단최가역치급기진단효력.결과 량명의사평분결과적Kappa치위0.80.질병조시선、합하선평분화총평분균명현고우대조조.시선、합하선평분화총평분적ROC곡선하면적분별위0.98、0.95、0.99,총평분적최가진단역치위8,진단민감성、특이성、양성예측치화음성예측치분별위93%、97%、95%、95%.결론 시선화합하선4개선체적초성평분법평개간조종합정연선병변구유교고적진단개치.
Objective To evaluate the diagnostic value of sonographic score in the diagnosis of salivary gland involvement in patients with Sj(o)gren's syndrome(SS). Methods One hundred and three cases (44 cases of SS group and 59 cases of control group) were involved in the study. Parotid and submandibular glands of all the cases were examined by a doctor unawaring of the clinical information. All the off-line images were scored by two doctors seperately. The best threshold and the according diagnostic efficiency were determined by statistical analysis. Results The Kappa coefficient between the two doctors was 0.80.The parotid score,submandibular score and total score of SS group were significantly higher than those of the control group (5.79 ± 2.40 vs 0.46 ± 0.97,5.93 ± 1.58 vs 1.32 ± 1.84,11.64 ± 3.27 vs 1.78 ± 2.33,respectively). According to the ROC curve for the parotid score, submandibular score and total score, the area under the curve were 0.98,0.95,0.99, respectively. The best diagnostic threshold for total score was 8 and under this threshold, the diagnostic sensitivity, specificity, positive and negative predictive values were 93%, 97%, 95%, 95%, respectively. Conclusions The sonographic score including both parotid and submandibular glands is a reliable method with high reproductivity and diagnostic accuracy in the diagnosis of SS salivary gland involvement.