中华脑血管病杂志（电子版）
中華腦血管病雜誌（電子版）
중화뇌혈관병잡지（전자판）
CHINESE JOURNAL OF CEREBROVASCULAR DISEASES(ELECTRONIC VERSION)
2012年
3期
24-28
,共5页
范蓉%辛世萌%范鸿博%薛俊燕
範蓉%辛世萌%範鴻博%薛俊燕
범용%신세맹%범홍박%설준연
脑梗死%复发%同型半胱氨酸%危险因素
腦梗死%複髮%同型半胱氨痠%危險因素
뇌경사%복발%동형반광안산%위험인소
Cerebral infarction%Recurrence%Homocysteine%Risk factor
探讨复发性脑梗死与血浆Hcy水平的关系.方法 100例急性脑梗死患者作为研究对象,50例非急性脑梗死患者作为对照组.将研究对象分为不同临床亚组、各类型急性脑梗死组、初发组与复发组,比较各组患者血浆Hcy水平及高Hcy比率.同时监测血压、血糖和血脂,对脑梗死的复发进行多因素分析.结果(1)脑梗死复发患者血浆Hcy水平高于初发患者(P＜0.01),且复发组高Hcy比率(54.45％)高于初发组(32.83％)(P＜0.05).(2)各类型急性脑梗死患者血浆Hcy水平均高于非急性脑梗死患者(P＜0.01)；各类型脑梗死患者之间血浆Hcy水平无显著性差异(P＞0.05).(3)1年内和1年后脑梗死复发患者血浆Hcy水平无显著性差异(P＞0.05).(4)各类型脑梗死复发患者之间血浆Hcy水平差异无显著性(P＞0.05)；血栓形成性脑梗死复发患者高Hcy比率略高于其他类型脑梗死(P＞0.05).(5)多因素分析显示脑梗死复发与高Hcy水平密切相关(P＜0.01).结论 高血浆Hcy水平是脑梗死复发的独立危险因素.
探討複髮性腦梗死與血漿Hcy水平的關繫.方法 100例急性腦梗死患者作為研究對象,50例非急性腦梗死患者作為對照組.將研究對象分為不同臨床亞組、各類型急性腦梗死組、初髮組與複髮組,比較各組患者血漿Hcy水平及高Hcy比率.同時鑑測血壓、血糖和血脂,對腦梗死的複髮進行多因素分析.結果(1)腦梗死複髮患者血漿Hcy水平高于初髮患者(P＜0.01),且複髮組高Hcy比率(54.45％)高于初髮組(32.83％)(P＜0.05).(2)各類型急性腦梗死患者血漿Hcy水平均高于非急性腦梗死患者(P＜0.01)；各類型腦梗死患者之間血漿Hcy水平無顯著性差異(P＞0.05).(3)1年內和1年後腦梗死複髮患者血漿Hcy水平無顯著性差異(P＞0.05).(4)各類型腦梗死複髮患者之間血漿Hcy水平差異無顯著性(P＞0.05)；血栓形成性腦梗死複髮患者高Hcy比率略高于其他類型腦梗死(P＞0.05).(5)多因素分析顯示腦梗死複髮與高Hcy水平密切相關(P＜0.01).結論 高血漿Hcy水平是腦梗死複髮的獨立危險因素.
탐토복발성뇌경사여혈장Hcy수평적관계.방법 100례급성뇌경사환자작위연구대상,50례비급성뇌경사환자작위대조조.장연구대상분위불동림상아조、각류형급성뇌경사조、초발조여복발조,비교각조환자혈장Hcy수평급고Hcy비솔.동시감측혈압、혈당화혈지,대뇌경사적복발진행다인소분석.결과(1)뇌경사복발환자혈장Hcy수평고우초발환자(P＜0.01),차복발조고Hcy비솔(54.45％)고우초발조(32.83％)(P＜0.05).(2)각류형급성뇌경사환자혈장Hcy수평균고우비급성뇌경사환자(P＜0.01)；각류형뇌경사환자지간혈장Hcy수평무현저성차이(P＞0.05).(3)1년내화1년후뇌경사복발환자혈장Hcy수평무현저성차이(P＞0.05).(4)각류형뇌경사복발환자지간혈장Hcy수평차이무현저성(P＞0.05)；혈전형성성뇌경사복발환자고Hcy비솔략고우기타류형뇌경사(P＞0.05).(5)다인소분석현시뇌경사복발여고Hcy수평밀절상관(P＜0.01).결론 고혈장Hcy수평시뇌경사복발적독립위험인소.
Objective To discuss the relationship between the recurrent cerebral infarction and plasma homocysteine.Metuods 100 patients hospitalized with acute cerebral infarction patients were selected as research subjects,and the other 50 patients with non-hospitalized patients without acute cerebral infarction were selected as a control group.100 patients were divided into different clinical subgroups-all types of acute cerebral infarction,the initial onset and relapse group.high plasma Hcy levels and Hcy ratio were compared among groups.At the same time routinely checked blood pressure,blood glucose andblood lipids,and also did a multivariate analysis of recurrence cerebral infarction.Results (1)Plasma Hcy levels in patients with recurrent cerebral infarction were higher than first onset patients(P ＜0.01); and the relapse rate of homocysteine group(54.45％)were also higher than onset group(32.83 ％),the difference was statistically significant(P ＜ 0.05).(2)Various types of plasma Hcy in patients with acute cerebral infarction was higher than non-acute cerebral infarction,the difference was statistically significant(P ＜0.01); various types of plasma Hcy levels between patients with cerebral infarction was no significant difference(P ＞ 0.05).(3)One year and one year after the plasma Hcy levels in patients with recurrent cerebral infarction was no significant difference(P ＞ 0.05).(4)Among various types of plasma Hcy in patients with recurrent cerebral infarction was no significant difference(P ＞ 0.05); recurrent thrombosis in patients with cerebral infarction rate slightly higher than the other types of high Hcy infarction(P ＞ 0.05).(5)Mutivariate analysis showed that cerebral infarction recurrence is closely related to high Hcy levels and (b)etes(p ＜ 0.01,P ＜ 0.05).Conclusions High plasma Hcy levels are independent risk factor for rec(re)nc of cerebral infarction.
