中国医药
中國醫藥
중국의약
CHINA MEDICINE
2010年
7期
596-597
,共2页
C反应蛋白质%急性冠状动脉综合征%甘油三酯类%胆固醇%高密度脂蛋白%胆固醇%低密度脂蛋白
C反應蛋白質%急性冠狀動脈綜閤徵%甘油三酯類%膽固醇%高密度脂蛋白%膽固醇%低密度脂蛋白
C반응단백질%급성관상동맥종합정%감유삼지류%담고순%고밀도지단백%담고순%저밀도지단백
C-reactive protein%Acute coronary syndrome%High density lopoprotein choelsterol%Low density lipoprotein cholesterol
目的 观察不同类型急性冠状动脉综合征(ACS)患者血清TG、HDL-C、LDL-C水平变化及其与高敏C反应蛋白(hs-CRP)的关系,探讨临床识别和预测ACS的指标.方法 将132例冠状动脉粥样硬化性心脏病(冠心病)患者分为ACS组和稳定型冠心病组(SCHD组),同时选择66例健康体检者作对照组,分别测定、比较3组的血清TG、HDL-C、LDL-C、hs-CRP水平.结果 ACS组和SCHD组患者血清hs-CRP水平[分别(9.26±10.98)mmol/L和(4.65±7.56)mmol/L]显著高于对照组[(1.21±1.32)mmol/L],差异有统计学意义(P＜0.05).ACS组血清hs-CRP水平显著高于和SCHD组,差异有统计学意义(P＜0.01).血清hs-CRP水平与TG含量呈显著正相关(r=0.62,P＜0.01),与LDL-C含量亦呈明显正相关(r=0.41,P＜0.01),与HDL-C含量呈显著负相关(r=-0.54,P＜0.01).结论 ACS患者血清hs-CRP水平显著增高;hs-CRP水平与ACS的严重程度呈正相关,是动脉粥样硬化斑块不稳定的标志.
目的 觀察不同類型急性冠狀動脈綜閤徵(ACS)患者血清TG、HDL-C、LDL-C水平變化及其與高敏C反應蛋白(hs-CRP)的關繫,探討臨床識彆和預測ACS的指標.方法 將132例冠狀動脈粥樣硬化性心髒病(冠心病)患者分為ACS組和穩定型冠心病組(SCHD組),同時選擇66例健康體檢者作對照組,分彆測定、比較3組的血清TG、HDL-C、LDL-C、hs-CRP水平.結果 ACS組和SCHD組患者血清hs-CRP水平[分彆(9.26±10.98)mmol/L和(4.65±7.56)mmol/L]顯著高于對照組[(1.21±1.32)mmol/L],差異有統計學意義(P＜0.05).ACS組血清hs-CRP水平顯著高于和SCHD組,差異有統計學意義(P＜0.01).血清hs-CRP水平與TG含量呈顯著正相關(r=0.62,P＜0.01),與LDL-C含量亦呈明顯正相關(r=0.41,P＜0.01),與HDL-C含量呈顯著負相關(r=-0.54,P＜0.01).結論 ACS患者血清hs-CRP水平顯著增高;hs-CRP水平與ACS的嚴重程度呈正相關,是動脈粥樣硬化斑塊不穩定的標誌.
목적 관찰불동류형급성관상동맥종합정(ACS)환자혈청TG、HDL-C、LDL-C수평변화급기여고민C반응단백(hs-CRP)적관계,탐토림상식별화예측ACS적지표.방법 장132례관상동맥죽양경화성심장병(관심병)환자분위ACS조화은정형관심병조(SCHD조),동시선택66례건강체검자작대조조,분별측정、비교3조적혈청TG、HDL-C、LDL-C、hs-CRP수평.결과 ACS조화SCHD조환자혈청hs-CRP수평[분별(9.26±10.98)mmol/L화(4.65±7.56)mmol/L]현저고우대조조[(1.21±1.32)mmol/L],차이유통계학의의(P＜0.05).ACS조혈청hs-CRP수평현저고우화SCHD조,차이유통계학의의(P＜0.01).혈청hs-CRP수평여TG함량정현저정상관(r=0.62,P＜0.01),여LDL-C함량역정명현정상관(r=0.41,P＜0.01),여HDL-C함량정현저부상관(r=-0.54,P＜0.01).결론 ACS환자혈청hs-CRP수평현저증고;hs-CRP수평여ACS적엄중정도정정상관,시동맥죽양경화반괴불은정적표지.
Objective To investigate the relation among triglyce ride (TG), low density lipoprotein cholesterol(LD-C) and high sensitivity C reactive protein(hs-CRP) in acute coronary syndrome(ACS). Methods A total of 132 coronary heart disease patients which were divided as ACS and stable coronary heart dis-ease(SCHD)groups and 65 cases of the health physical exam inees were enrolled as the controls. The levels of hs-CRP, TG,HDL-C and LDL-C among the three groups were analyzed. Results The levels of hs-CRP of patients in ACS and SCHD groups were significantly higher than those in controls group(P ＜0.05). The level of hs-CRP in ACS group was obviously higher than that in SCHD group( P ＜0.01 ). There was a significant correlation between the concentration of hsCRP and TG( r = 0.62 ,P ＜ 0.01 ); there was a significant correlation between hs-CRPand LDL-C ( r =0.41, P ＜ 0.01 ); however there was a significantly negative correlation between hs-CRP and HDL-C ( r = -0.54, P ＜0.01 ). Conclusions The hs-CRP level in patients with acute coronary syndrome is obviously increased. hs-CRP is positively correlated with acute coronary syndrome, hs-CRP is the unstable sign of atheromatous plaque.
