CAJ | 학술논문

目的分析脓毒症休克患者血管外肺水(EVLW)的变化特点,探讨其与脓毒症休克预后的关系.方法采用回顾性分析的方法,将21例脓毒症休克患者根据最终临床转归分为存活组(10例)与死亡组(11例),观察两组患者的临床特征,利用脉波指示剂连续心排血量(PiCCO)监护仪进行血流动力学监测,测定EVLW,分析其与患者预后的关系.结果存活组入院第1、2、3天EVLW分别为(12.7±1.8)、(11 3±1.3)、(10.1±1.3)ml/kg,死亡组分别为(14.4±1.0)、(14.6±1.4)、(14.6±1.3)ml/kg,两组比较差异有统计学意义(P＜0.05);存活组随入院时间延长EVLW均明显下降(P＜0.05),死亡组无明显变化(P＞0.05).结论脓毒症休克患者EVLW均有明显增加;EVLW的动态变化可预测患者的预后.
목적 분석농독증휴극환자혈관외폐수(EVLW)적변화특점,탐토기여농독증휴극예후적관계.방법 채용회고성분석적방법,장21례농독증휴극환자근거최종림상전귀분위존활조(10례)여사망조(11례),관찰량조환자적림상특정,이용맥파지시제련속심배혈량(PiCCO)감호의진행혈류동역학감측,측정EVLW,분석기여환자예후적관계.결과 존활조입원제1、2、3천EVLW분별위(12.7±1.8)、(11 3±1.3)、(10.1±1.3)ml/kg,사망조분별위(14.4±1.0)、(14.6±1.4)、(14.6±1.3)ml/kg,량조비교차이유통계학의의(P＜0.05);존활조수입원시간연장EVLW균명현하강(P＜0.05),사망조무명현변화(P＞0.05).결론 농독증휴극환자EVLW균유명현증가;EVLW적동태변화가예측환자적예후.
Objective To analyze the alterative characteristics of the extravascular lung water (EVLW ) in the patients with septic shock and clarify its value on the prognosis of these patients.Methods By the methods of retrospective analysis,according to the ultimate survival,21 patients with septic shock were divided into survivor group (10 cases) and non-survivor group (11 cases).The clinical features of the patients were observed and hemodynamic monitoring was made with PiCCO monitor.The EVLW was measured and the relationship between the EVLW and the prognosis of patients was analyzed.Results On the first,second and third day,EVLW was (12.7 ±1.8),(11.3 ±1.3),(10.1 ±1.3) ml/kg in survivor group,and (14.4 ± 1.0),(14.6 ± 1.4),(14.6 ±1.3) ml/kg in non-survivor group respectively,and there were statistical differences between two groups (P <0.05).However,on the second day after the intensive therapy,EVLW in survivor group dropped significantly(P＜0.05),but the non-survivor group only declined slightly,and compared with the result of the first day,there was no obvious difference (P >0.05).Conclusions The EVLW in the patients with septic shock increases significantly.The dynamic changes of the EVLW may be one of the factors for predicting the prognosis of patients with septic shock.