中华眼底病杂志
中華眼底病雜誌
중화안저병잡지
CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
2010年
4期
335-338
,共4页
孙堂胜%阿西木江%魏世辉
孫堂勝%阿西木江%魏世輝
손당성%아서목강%위세휘
色觉缺陷/病理生理学%视神经炎/并发症%视神经炎/治疗%色觉试验/利用
色覺缺陷/病理生理學%視神經炎/併髮癥%視神經炎/治療%色覺試驗/利用
색각결함/병리생이학%시신경염/병발증%시신경염/치료%색각시험/이용
Color vision defects/pathophysiology%Optic neuritis/complications%Optic neuritis/therapy%Color perception tests/utilization
目的 观察特发性视神经炎(ION)患者治疗后色觉损害情况.方法 临床确诊的ION患者26例44只眼纳入本研究.所有患者均经糖皮质激素类药物大剂量冲击治疗,治疗后视力恢复至1.0以上,神经系统MRI及血液检查等无异常.另选取24名健康体检者作为正常对照组.ION患者治疗后8～10周,平均(9.64±1.39)周后进行色觉检查.采用Farnsworth Munsell-100型色觉测试仪检测ION患者患眼的总错误得分及红、绿、蓝各色彩的错误得分,原值及取平方根后进行统计学分析;并与对照组色觉检测结果进行比较.结果 ION组总错误得分及总错误得分平方根与对照组相比,差异均有统计学意义(t=3.079,3.133;P=0.0033,0.0026).红、绿、蓝3种色彩错误得分在原值水平比较分析时,两组差异无统计学意义(t=1.91,1.15,1.62;P=0.061,0.26,0.11),但将原值平方根后显示2组红色觉得分差异有统计学意义(t=2.21,P=0.031).结论 ION患者经治疗后虽然视力恢复,但其色觉损害仍然存在,其中红色觉在视力恢复后最早出现明显损害.
目的 觀察特髮性視神經炎(ION)患者治療後色覺損害情況.方法 臨床確診的ION患者26例44隻眼納入本研究.所有患者均經糖皮質激素類藥物大劑量遲擊治療,治療後視力恢複至1.0以上,神經繫統MRI及血液檢查等無異常.另選取24名健康體檢者作為正常對照組.ION患者治療後8～10週,平均(9.64±1.39)週後進行色覺檢查.採用Farnsworth Munsell-100型色覺測試儀檢測ION患者患眼的總錯誤得分及紅、綠、藍各色綵的錯誤得分,原值及取平方根後進行統計學分析;併與對照組色覺檢測結果進行比較.結果 ION組總錯誤得分及總錯誤得分平方根與對照組相比,差異均有統計學意義(t=3.079,3.133;P=0.0033,0.0026).紅、綠、藍3種色綵錯誤得分在原值水平比較分析時,兩組差異無統計學意義(t=1.91,1.15,1.62;P=0.061,0.26,0.11),但將原值平方根後顯示2組紅色覺得分差異有統計學意義(t=2.21,P=0.031).結論 ION患者經治療後雖然視力恢複,但其色覺損害仍然存在,其中紅色覺在視力恢複後最早齣現明顯損害.
목적 관찰특발성시신경염(ION)환자치료후색각손해정황.방법 림상학진적ION환자26례44지안납입본연구.소유환자균경당피질격소류약물대제량충격치료,치료후시력회복지1.0이상,신경계통MRI급혈액검사등무이상.령선취24명건강체검자작위정상대조조.ION환자치료후8～10주,평균(9.64±1.39)주후진행색각검사.채용Farnsworth Munsell-100형색각측시의검측ION환자환안적총착오득분급홍、록、람각색채적착오득분,원치급취평방근후진행통계학분석;병여대조조색각검측결과진행비교.결과 ION조총착오득분급총착오득분평방근여대조조상비,차이균유통계학의의(t=3.079,3.133;P=0.0033,0.0026).홍、록、람3충색채착오득분재원치수평비교분석시,량조차이무통계학의의(t=1.91,1.15,1.62;P=0.061,0.26,0.11),단장원치평방근후현시2조홍색각득분차이유통계학의의(t=2.21,P=0.031).결론 ION환자경치료후수연시력회복,단기색각손해잉연존재,기중홍색각재시력회복후최조출현명현손해.
Objective To detect the color damage in patients with idiopathic optical neuritis (ION) after the treatment. Methods A total of 26 ION patients (44 eyes) with ION whose visual acuity were above 1. 0 were collected. All the patients had undergone the treatment of incretion and had the visual acuity more than 1. 0 after the treatment. The results of MRI and blood examination were normal. Another 24 healthy persons were selected as the normal control. Total error scores (TES) and each error score of red, green and blue were measured via Farnsworth Munsell-100 hue tester. The TES origin scores and their square roots were used for a statistical analysis. The results of the two groups were compared. Results There were significant differences in TES and its square roots between ION group and the normal control group (t=3.079,3. 133;P = 0. 0033,0. 0026). The differences in the level of error scores of each color between the tow groups were not significant (t = 1. 91, 1.15, 1.62;P = 0.061, 0.26, 0.11);but the differences in the square roots of red color between the two groups were statistically (t=2. 21, P = 0. 031).Conclusion After the treatment, the visual acuity of ION patients increases, but the color damage still exist;red color damage happens first.
