CAJ | 학술논문

目的探讨机械式过滤器应用于机械通气患者的安全性.方法选择机械通气并常规气道湿化患者60例,随机分成两组,30例加用机械式过滤器治疗者为治疗组,另30例未使用过滤器者为对照组.观察两组患者呼吸功能(机械通气第l天的2 h、12 h、24 h的气道平台压力、内源性呼气末正压及动脉血二氧化碳分压)的变化、呼吸机相关性肺炎的发生率和病死率.结果机械式过滤器在临床使用过程中不会增加患者呼吸道阻力,不增加患者呼吸做功,未发生因阻塞而引起的高碳酸血症;机械式过滤器使用后呼吸机相关性肺炎发生率明显低于对照组(26.7%与56.7%,x2=5.554,P=0.018).结论机械式过滤器可安全用于机械通气患者,并降低呼吸机相关性肺炎发生率.
목적 탐토궤계식과려기응용우궤계통기환자적안전성.방법 선택궤계통기병상규기도습화환자60례,수궤분성량조,30례가용궤계식과려기치료자위치료조,령30례미사용과려기자위대조조.관찰량조환자호흡공능(궤계통기제l천적2 h、12 h、24 h적기도평태압력、내원성호기말정압급동맥혈이양화탄분압)적변화、호흡궤상관성폐염적발생솔화병사솔.결과 궤계식과려기재림상사용과정중불회증가환자호흡도조력,불증가환자호흡주공,미발생인조새이인기적고탄산혈증;궤계식과려기사용후호흡궤상관성폐염발생솔명현저우대조조(26.7%여56.7%,x2=5.554,P=0.018).결론 궤계식과려기가안전용우궤계통기환자,병강저호흡궤상관성폐염발생솔.
Objective To investigate the security of mechanical filter in mechanical ventilation for ICU patients.Methods 60 patients treated with mechanical ventilation and conventional airway humidification were selected and randomly divided into treatment group(mechanical filter treatment) and control group(non filter treatment) ,30 cases in each group.The changes of respiratory function(airway plateau pressure,endogenous PEEP and arterial carbon dioxide partial pressure of 2h,12h,24h at the first day of mechanical ventilation) ,and the incidence and mortality of ventilator-associated pneumonia were observed.Results The study showed airway resistance and the work of breathing in treatment group did not increase,and no hypercapnia due to congestion occurred.The incidence of ventilator-associated pneumonia in treatment group was significantly lower than that of the control group (26.7% vs 56.7% ,x2 = 5.554,P = 0.018).Conclusion Mechanical filer applied in patients with mechanical ventilation was safe and could decrease the incidence of ventilator-associated pneumonia.