中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2008年
25期
20-22
,共3页
顾俊%胡伟%肖红兵%冯小弟%金贤%余强%尹桂芝%关平%陈诚军%陈跃光%张大东
顧俊%鬍偉%肖紅兵%馮小弟%金賢%餘彊%尹桂芝%關平%陳誠軍%陳躍光%張大東
고준%호위%초홍병%풍소제%금현%여강%윤계지%관평%진성군%진약광%장대동
心肌梗死%血管成形术,经腔,经皮冠状动脉%预后%替罗非班
心肌梗死%血管成形術,經腔,經皮冠狀動脈%預後%替囉非班
심기경사%혈관성형술,경강,경피관상동맥%예후%체라비반
Myocardial infarction%Angioplasty,transluminal,percutaneous coronary%Prognosis%Tirofiban
目的 评价急性ST段抬高心肌梗死(STEMI)患者直接经皮冠状动脉介入治疗(PCI)后应用替罗非班时间对中期临床预后的影响.方法 选择50例急性STEMI患者入院后即刻接受、替罗非班治疗,直接PCI后随机分为两组:短时间组(STG,PCI后替罗非班继续使用24～36 h)29例和长时间组(LTG,PCI后替罗非班继续使用48-72 h)21例.记录两组患者随访6个月内主要心脏不良事件和术后6个月复查冠状动脉造影结果.结果 LTG患者随访期间顽固性心绞痛的发生率为14.3%,明显低于STG患者的24.1%(P<0.05),但两组的再狭窄率比较差异无统计学意义.结论 急性STEMI患者急诊直接PCI后较长时间应用替罗非班可减少顽固性心绞痛的发生,改善中期临床预后.
目的 評價急性ST段抬高心肌梗死(STEMI)患者直接經皮冠狀動脈介入治療(PCI)後應用替囉非班時間對中期臨床預後的影響.方法 選擇50例急性STEMI患者入院後即刻接受、替囉非班治療,直接PCI後隨機分為兩組:短時間組(STG,PCI後替囉非班繼續使用24～36 h)29例和長時間組(LTG,PCI後替囉非班繼續使用48-72 h)21例.記錄兩組患者隨訪6箇月內主要心髒不良事件和術後6箇月複查冠狀動脈造影結果.結果 LTG患者隨訪期間頑固性心絞痛的髮生率為14.3%,明顯低于STG患者的24.1%(P<0.05),但兩組的再狹窄率比較差異無統計學意義.結論 急性STEMI患者急診直接PCI後較長時間應用替囉非班可減少頑固性心絞痛的髮生,改善中期臨床預後.
목적 평개급성ST단태고심기경사(STEMI)환자직접경피관상동맥개입치료(PCI)후응용체라비반시간대중기림상예후적영향.방법 선택50례급성STEMI환자입원후즉각접수、체라비반치료,직접PCI후수궤분위량조:단시간조(STG,PCI후체라비반계속사용24～36 h)29례화장시간조(LTG,PCI후체라비반계속사용48-72 h)21례.기록량조환자수방6개월내주요심장불량사건화술후6개월복사관상동맥조영결과.결과 LTG환자수방기간완고성심교통적발생솔위14.3%,명현저우STG환자적24.1%(P<0.05),단량조적재협착솔비교차이무통계학의의.결론 급성STEMI환자급진직접PCI후교장시간응용체라비반가감소완고성심교통적발생,개선중기림상예후.
Objective To investigate the effects of tirofiban application time on middle-term clinical prognosis in patients with acute ST segment elevation myocardial infarction (STEMI)treated by primary percutsneous coronary intervention (PCI). Methods The study of tirofiban was carried out in 50 patients with STEM[in cardiology department from January to December 2006. Twenty-nine patients were randomized to receive tirofiban after PCI for 24 - 36 hours(short time group, STG) and 21 patients for 48 - 72 hours (long time group,LTG). Clinical characteristics, angiography data, main adverse cardiovascular events (MACE) and coronary restenosis rate in 6-month follow-up of the two groups were. compared. Results Follow-up data showed that there was less intractable angina pectoris (14.3% vs 24.1%, P< 0.05) in LTG. But there was no significant difference in coronary restenosis rate between two groups. Conclusion Long time application of tirofiban following PCI in patients with STEMI could improve middle-term clinical prognosis by alleviating the incidence of intractable angina pectoris.
