中华精神科杂志
中華精神科雜誌
중화정신과잡지
CHINESE JOURNA OF PSYCHIATRY
2012年
3期
154-160
,共7页
那祖克·玉素甫%朱沂%曼古努尔·玉山%艾比拜·努尔买买提
那祖剋·玉素甫%硃沂%曼古努爾·玉山%艾比拜·努爾買買提
나조극·옥소보%주기%만고노이·옥산%애비배·노이매매제
认知障碍%认知%信度%效度%蒙特利尔认知评估量表
認知障礙%認知%信度%效度%矇特利爾認知評估量錶
인지장애%인지%신도%효도%몽특리이인지평고량표
Cognition disorders%Cognition%Reliability%Validity%Montreal cognitive assessment
目的 对维吾尔文版蒙特利尔认知评估量表( MoCA-U)在乌鲁木齐地区维吾尔族人群中应用的信度及效度进行检验,并初步确定该量表筛查维吾尔族认知障碍人群的最佳界值.方法 对英文版MoCA量表进行翻译并修订成维吾尔文版,选择188名50～75岁的维吾尔族研究对象,其中正常对照组80名、轻度认知功能障碍(MCI)组68例、痴呆组40例,分别用MoCA-U、简易精神状态量表(MMSE)、临床痴呆量表(CDR)等神经心理学量表进行评估比较.结果 (1)MoCA-U的克朗巴赫α系数为0.801,评定者间一致性组内相关系数为=0.977(95％可信区间;0.949～0.990),重测信度r =0.987(P ＜0.001).(2)正常对照组、MCI组、痴呆组的MoCA-U总分分别为(22.65±2.57)、(18.56±3.08)、(9.43±3.89)分,3组比较差异有统计学意义(F=27.991,P＜0.001)；MoCA-U与MMSE、CDR量表总分的相关系数分别为r=0.84(P ＜0.001)和r=-0.77(P ＜0.001).(3)当研究对象受教育年限≤5年时,MoCA-U筛查MCI的最佳界值为20分,此时MoCA-U灵敏度为86.4％,特异度为84.2％；筛查痴呆的最佳界值为13分,此时的灵敏度为94.1％、特异度为100％.受教育年限6～10年时,MoCA-U筛查MCI的最佳界值为21分,灵敏度为84.6％,特异度为94.1％；筛查痴呆的最佳界值为15分,此时的灵敏度为100％,特异度为92.3％.受教育年限≥11年时,MoCA-U筛查MCI的最佳界值为22分,灵敏度为75.8％,特异度为70.5％；筛查痴呆的最佳界值为17分,此时的灵敏度为100％,特异度为84.8％.结论 MoCA-U具有良好的信效度及可行性,适合对乌鲁木齐中老年维吾尔族人群认知功能进行评估；不同受教育程度人群筛查MCI的最佳界值为20～22分,筛查痴呆的最佳界值为13～17分.
目的 對維吾爾文版矇特利爾認知評估量錶( MoCA-U)在烏魯木齊地區維吾爾族人群中應用的信度及效度進行檢驗,併初步確定該量錶篩查維吾爾族認知障礙人群的最佳界值.方法 對英文版MoCA量錶進行翻譯併脩訂成維吾爾文版,選擇188名50～75歲的維吾爾族研究對象,其中正常對照組80名、輕度認知功能障礙(MCI)組68例、癡呆組40例,分彆用MoCA-U、簡易精神狀態量錶(MMSE)、臨床癡呆量錶(CDR)等神經心理學量錶進行評估比較.結果 (1)MoCA-U的剋朗巴赫α繫數為0.801,評定者間一緻性組內相關繫數為=0.977(95％可信區間;0.949～0.990),重測信度r =0.987(P ＜0.001).(2)正常對照組、MCI組、癡呆組的MoCA-U總分分彆為(22.65±2.57)、(18.56±3.08)、(9.43±3.89)分,3組比較差異有統計學意義(F=27.991,P＜0.001)；MoCA-U與MMSE、CDR量錶總分的相關繫數分彆為r=0.84(P ＜0.001)和r=-0.77(P ＜0.001).(3)噹研究對象受教育年限≤5年時,MoCA-U篩查MCI的最佳界值為20分,此時MoCA-U靈敏度為86.4％,特異度為84.2％；篩查癡呆的最佳界值為13分,此時的靈敏度為94.1％、特異度為100％.受教育年限6～10年時,MoCA-U篩查MCI的最佳界值為21分,靈敏度為84.6％,特異度為94.1％；篩查癡呆的最佳界值為15分,此時的靈敏度為100％,特異度為92.3％.受教育年限≥11年時,MoCA-U篩查MCI的最佳界值為22分,靈敏度為75.8％,特異度為70.5％；篩查癡呆的最佳界值為17分,此時的靈敏度為100％,特異度為84.8％.結論 MoCA-U具有良好的信效度及可行性,適閤對烏魯木齊中老年維吾爾族人群認知功能進行評估；不同受教育程度人群篩查MCI的最佳界值為20～22分,篩查癡呆的最佳界值為13～17分.
목적 대유오이문판몽특리이인지평고량표( MoCA-U)재오로목제지구유오이족인군중응용적신도급효도진행검험,병초보학정해량표사사유오이족인지장애인군적최가계치.방법 대영문판MoCA량표진행번역병수정성유오이문판,선택188명50～75세적유오이족연구대상,기중정상대조조80명、경도인지공능장애(MCI)조68례、치태조40례,분별용MoCA-U、간역정신상태량표(MMSE)、림상치태량표(CDR)등신경심이학량표진행평고비교.결과 (1)MoCA-U적극랑파혁α계수위0.801,평정자간일치성조내상관계수위=0.977(95％가신구간;0.949～0.990),중측신도r =0.987(P ＜0.001).(2)정상대조조、MCI조、치태조적MoCA-U총분분별위(22.65±2.57)、(18.56±3.08)、(9.43±3.89)분,3조비교차이유통계학의의(F=27.991,P＜0.001)；MoCA-U여MMSE、CDR량표총분적상관계수분별위r=0.84(P ＜0.001)화r=-0.77(P ＜0.001).(3)당연구대상수교육년한≤5년시,MoCA-U사사MCI적최가계치위20분,차시MoCA-U령민도위86.4％,특이도위84.2％；사사치태적최가계치위13분,차시적령민도위94.1％、특이도위100％.수교육년한6～10년시,MoCA-U사사MCI적최가계치위21분,령민도위84.6％,특이도위94.1％；사사치태적최가계치위15분,차시적령민도위100％,특이도위92.3％.수교육년한≥11년시,MoCA-U사사MCI적최가계치위22분,령민도위75.8％,특이도위70.5％；사사치태적최가계치위17분,차시적령민도위100％,특이도위84.8％.결론 MoCA-U구유량호적신효도급가행성,괄합대오로목제중노년유오이족인군인지공능진행평고；불동수교육정도인군사사MCI적최가계치위20～22분,사사치태적최가계치위13～17분.
Objective To evaluate the reliability and validity of Uyghur version of the Montreal Cognitive Assessment ( MoCA-U ) among the Uyghur people in Urumqi,and determine the optimal cutoff score of MoCA-U to detect the cognitive impairment in the Uyghur people.Methods The English MoCA was translated and adapted into the Uyghur version.The MoCA-U,MMSE,CDR and other neuropsychological batteries were administered to 188 Uyghur people who were aged 50 -75,80 of them were in the normal cognitive group,68 of them were in the mild cognitive impairment(MCI) group and 40 of them were in the dementia group.Results ( 1 ) Cronbach＇s α of MoCA-U was 0.801,inter-rater reliability ICC was 0.977 ( 95％ CI:0.949 - 0.990 ),test-retest reliability r was 0.987 ( P ＜ 0.001 ).( 2 ) The MoCA-U scores of 3 groups were normal cognitive ( 22.65 ± 2.57 ),MCI ( 18.56 ± 3.08 ) and dementia( 9.43 ± 3.89 ),were significantly different among the 3 groups ( F =27.991,P ＜ 0.001 ).The correlation coefficients of the scores of MoCA-U with those of MMSE and CDR were r =0.84 ( P ＜ 0.001 ) and r =- 0.77 ( P ＜ 0.001 ).(3) MoCA-U scores in the participants with 5 years of education or less,using a cutoff score of 20,the MoCA-U had a sensitivity of 86.4％ and a specificity of 84.2％ for screening MCI,and using a cutoff score of 13,the MoCA-U had a sensitivity of 94.1％ and a specificity of 100％ to detect dementia.In the participants within 6 - 10 years of education,using a cutoff score of 21,the MoCA-U had a sensitivity of 84.6％ and a specificity of 94.1％ for screening MCI,and using a cutoff score of 15,the MoCA-U had a sensitivity of 100％ and a specificity of 92.3％ to detect dementia.In the participants with more than 11 years of education,using a cutoff score of 22,the MoCA-U had a sensitivity of 75.8％ and a specificity of 70.5％ for screening MCI,using a cutoff score of 17,the MoCA-U had a sensitivity of 100％ and a specificity of 84.8％ to detect dementia.Conclusion The MoCA-U has a good reliability,validity and feasibility,and is suitable for use as a screening tool to screen cognitive function in elderly Uyghur people in Urumqi.The optimal cutoff score for different education years to screen MCI is 20-22,screen dementia is 13 -17.
