CAJ | 학술논문

目的观察不同程度精索静脉曲张(VC)患者精液质量及精子形态.方法 121例VC患者分为Ⅰ、Ⅱ、Ⅲ度共3组,其精液按WHO标准常规分析并对精子形态进行评价,23例健康男性精液检查结果作为对照.结果不同程度VC患者与对照组比较,精液各项常规指标及正常形态精子百分率均下降(P<0.01),畸形精子中,小头、锥形头和无定形头精子均增多(P<0.01,P<0.05,P<0.01).不同程度VC患者间比较,常规检查各项指标无明显差异(P>0.05),形态检查Ⅲ度VC组正常形态精子百分率低于Ⅱ度VC组(P<0.01),而Ⅱ度VC组与Ⅰ度VC组差异无统计学意义(P>0.05).具体畸形精子类别比较,Ⅲ度VC组的无定形精子百分率明显高于Ⅱ度VC组(P<0.01).结论精液常规检查不能区分不同程度VC对精液损害的影响,而精子形态检查可反映不同程度VC患者的精子状态.因此,VC患者不但应行精液常规检查还应行精子形态检查.
목적 관찰불동정도정색정맥곡장(VC)환자정액질량급정자형태.방법 121례VC환자분위Ⅰ、Ⅱ、Ⅲ도공3조,기정액안WHO표준상규분석병대정자형태진행평개,23례건강남성정액검사결과작위대조.결과 불동정도VC환자여대조조비교,정액각항상규지표급정상형태정자백분솔균하강(P<0.01),기형정자중,소두、추형두화무정형두정자균증다(P<0.01,P<0.05,P<0.01).불동정도VC환자간비교,상규검사각항지표무명현차이(P>0.05),형태검사Ⅲ도VC조정상형태정자백분솔저우Ⅱ도VC조(P<0.01),이Ⅱ도VC조여Ⅰ도VC조차이무통계학의의(P>0.05).구체기형정자유별비교,Ⅲ도VC조적무정형정자백분솔명현고우Ⅱ도VC조(P<0.01).결론 정액상규검사불능구분불동정도VC대정액손해적영향,이정자형태검사가반영불동정도VC환자적정자상태.인차,VC환자불단응행정액상규검사환응행정자형태검사.
Objective To evaluate the semen quality and sperm morphology in the patients with different grades of varicocele. Methods Semen from 121 patients with varicocele which were divided into three groups, gradel, grade Ⅱ and grade Ⅲ, were studied and those of 23 normal male were taken as the control. Semen analysis was performed with the methods described in the WHO manual and sperm morphology was evaluated by WHO cri-teria. Results A significant reduction of semen quality and sperm morphology and an increase of small oval head, tapering head and amorphous head sperm were found in patients with different grades of varicocele compa-ring with those of the control. There was no difference in routine analysis between different groups. A reducetion of normal morphology percentage in grade Ⅲ were found comparing with grade Ⅱ (P<0.01). An increase of a-morphous head sperm in grade Ⅲ was found comparing with that of sperm in grade Ⅱ (P <0.01). Canclusions The routine semen analysis can not distinguish seminal damage between different grades of varicocele, but the sperm morphology can reflect the sperm state. Therefore, the patients with varicocele should not only get routine semen analysis but also check the sperm morphology.