CAJ | 학술논문

妊娠糖尿病包括糖尿病合并妊娠以及妊娠期糖尿病,其发病率呈逐年上升趋势.妊娠糖尿病对后代的生长发育、健康状况有诸多不良影响.与健康母亲后代相比,妊娠糖尿病母亲后代出生体重较重,儿童期及青春期易出现肥胖,智力和神经行为发育也会受到不良影响.随年龄增长,妊娠糖尿病母亲后代的物质代谢调节能力下降,心血管疾病的危险因素增加,各种代谢性疾病及慢性病的发生风险及发生率亦升高.目前学术界较为接受的妊娠糖尿病对后代造成影响的机理是"胎源性疾病"假说,其具体机制有待进一步探索.积极发现并控制妊娠期糖代谢异常,对优生优育,减少远瑚卫生经济投入有巨大价值.
임신당뇨병포괄당뇨병합병임신이급임신기당뇨병,기발병솔정축년상승추세.임신당뇨병대후대적생장발육、건강상황유제다불량영향.여건강모친후대상비,임신당뇨병모친후대출생체중교중,인동기급청춘기역출현비반,지력화신경행위발육야회수도불량영향.수년령증장,임신당뇨병모친후대적물질대사조절능력하강,심혈관질병적위험인소증가,각충대사성질병급만성병적발생풍험급발생솔역승고.목전학술계교위접수적임신당뇨병대후대조성영향적궤리시"태원성질병"가설,기구체궤제유대진일보탐색.적겁발현병공제임신기당대사이상,대우생우육,감소원호위생경제투입유거대개치.
There are two kinds of diabetes in pregnancy:diabetes complicated with pregnancy and gestational diabetes mellitus(GDM).The prevalence of diabetes in pregnancy is increasing.In the long term,diabetes in pregnancy may harmfully influence the health,growth and development of the offspring.Compared with the offspring of healthy mothers,the offspring of diabetic mothers are heavier at birth,and will become more obese during their childhood and adolescence.Their intelligence and neurobehavioral development are also influenced.As time goes by,the offspring of diabetic mothers have a decreasing ability of metabolic control,thus the risk and prevalence of metabolic diseases and cardiovascular diseases are also increased.At present,the mechanism of the harmful influence of diabetes in pregnancy is well accepted by the academic circles as the "fetal original diseases"hypothesis.the research of more details is necessary.It will benefit a lot from screening and treating the glucose metabolic disorder during pregnancy.