国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2010年
8期
597-600
,共4页
肺肿瘤%TNF相关凋亡诱导配体%细胞凋亡
肺腫瘤%TNF相關凋亡誘導配體%細胞凋亡
폐종류%TNF상관조망유도배체%세포조망
Lung neoplasms%TNF-related apoptosis-inducing ligand%Apoptosis
肿瘤坏死因子相关凋亡诱导配体(TRAIL)是近年新发现的一种凋亡诱导配体,可以激活多信号传导途径诱导肿瘤细胞凋亡,而对正常细胞没有杀伤作用.TRAIL能诱导肺肿瘤细胞发生凋亡而对正常细胞没有毒性,这为肺癌的治疗提供了新的途径.
腫瘤壞死因子相關凋亡誘導配體(TRAIL)是近年新髮現的一種凋亡誘導配體,可以激活多信號傳導途徑誘導腫瘤細胞凋亡,而對正常細胞沒有殺傷作用.TRAIL能誘導肺腫瘤細胞髮生凋亡而對正常細胞沒有毒性,這為肺癌的治療提供瞭新的途徑.
종류배사인자상관조망유도배체(TRAIL)시근년신발현적일충조망유도배체,가이격활다신호전도도경유도종류세포조망,이대정상세포몰유살상작용.TRAIL능유도폐종류세포발생조망이대정상세포몰유독성,저위폐암적치료제공료신적도경.
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a newly discovered apoptosis-inducing ligand that can induce apoptosis of cancer cells, but not of normal cells, through the activation of multiple signaling transduction pathways. By sensitizing lung cancer cells but not normal cells to apoptosis,TRAIL may become a new strategy for the treatment of lung cancer.
