CAJ | 학술논문

全球范围内有超过4亿慢性乙型肝炎病毒携带者,这些患者发展为肝硬化和肝癌的危险性较大.现有疗法不能长期控制大多数患者的病毒复制,而治疗性乙型肝炎疫苗因其独特的优点正成为新的研究热点.此文就治疗性乙型肝炎疫苗的分类及最新研究进展加以综述.
전구범위내유초과4억만성을형간염병독휴대자,저사환자발전위간경화화간암적위험성교대.현유요법불능장기공제대다수환자적병독복제,이치료성을형간염역묘인기독특적우점정성위신적연구열점.차문취치료성을형간염역묘적분류급최신연구진전가이종술.
More than 400 million people in the world are now chronically infected with hepatitis B virus(HBV). For these patients, there is a high risk to develop cirrhosis and hepatocellular carcinoma. Currently available therapies fail to control viral replication for a long time in most patients. Vaccine therapy has recently shown a unique advantage and become the development focus for treatment of patients with chronic HBV infection. This paper reviews the classification and recent research progress of therapeutic HBV vaccines.