国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2009年
12期
932-934
,共3页
老年人%癌%非小细胞肺%靶向治疗
老年人%癌%非小細胞肺%靶嚮治療
노년인%암%비소세포폐%파향치료
Aged%Carcinoma%non-small-cell lung%Targeted therapy
随着肿瘤细胞生物学的进展,已研制出许多针对特异性分子靶向的治疗药物,而且在晚期非细胞肺癌患者的一线和二线治疗中均已显示出较好的疗效,由于老年患者有着生理学、药理学等各方面的特点,对化疗耐受性差,而针对此类患者的分子靶向治疗具有重要临床价值.
隨著腫瘤細胞生物學的進展,已研製齣許多針對特異性分子靶嚮的治療藥物,而且在晚期非細胞肺癌患者的一線和二線治療中均已顯示齣較好的療效,由于老年患者有著生理學、藥理學等各方麵的特點,對化療耐受性差,而針對此類患者的分子靶嚮治療具有重要臨床價值.
수착종류세포생물학적진전,이연제출허다침대특이성분자파향적치료약물,이차재만기비세포폐암환자적일선화이선치료중균이현시출교호적료효,유우노년환자유착생이학、약이학등각방면적특점,대화료내수성차,이침대차류환자적분자파향치료구유중요림상개치.
With the development of tumor cell biology,many targeted therapy drugs that aim specifically to inhibit tumor growth have been developed. Application of targeted drugs as first-line and second-line therapy in patients with advanced non-small cell lung cancer (NSCLC) have acquired exciting curative effect. Molecular targeted therapy for old patients have important clinical values,because old patients have weak toleration to chemotherapy as a result of physical and pharmacological features.