CAJ | 학술논문

目的掌握青海省贵德县地方性氟中毒病情与流行状况,进一步做好氟中毒监测防控工作.方法 2008年,选择贵德县大磨、温泉、保宁村(已改水村)和太平村(未改水村),分别采集枯水期和丰水期末梢水样各1份,按照<生活饮用水标准检验方法>(GB/T 5750.5-2006)检测水氟;对全部8～12岁儿童采用Dean法进行氟斑牙检查,每个年龄组抽检6人采集尿样,用氟离子选择电极法(WS/T 89-1996)检测尿氟;按照<地方性氟骨症诊断标准>(WS 192-2008),对16岁以上成人进行临床氟骨症检查,每个村抽取男女各10人,进行氟骨症X线诊断.结果大磨、温泉、太平、保宁4个村水氟均值分别为0.58、0.38、2.28、0.57 mg/L,其中太平村水氟均值超过国家生活饮用水卫生标准(1.0 mg/L).共检查8～12岁儿童193人,儿童氟斑牙检出率为49.74%(96/193);共检测儿童尿样116份,尿氟中位数为1.49 mg/L.共检查16岁以上成人1503人,临床氟骨症检出率为51.63%(776/1503);共对82人进行X线拍片,X线氟骨症检出率为20.73%(17/82),X线表现以关节退行性改变及骨间膜骨化为主.结论贵德县儿童氟斑牙和成人临床氟骨症检出率较高,氟中毒流行较重,防治形势刻不容缓.
목적 장악청해성귀덕현지방성불중독병정여류행상황,진일보주호불중독감측방공공작.방법 2008년,선택귀덕현대마、온천、보저촌(이개수촌)화태평촌(미개수촌),분별채집고수기화봉수기말소수양각1빈,안조<생활음용수표준검험방법>(GB/T 5750.5-2006)검측수불;대전부8～12세인동채용Dean법진행불반아검사,매개년령조추검6인채집뇨양,용불리자선택전겁법(WS/T 89-1996)검측뇨불;안조<지방성불골증진단표준>(WS 192-2008),대16세이상성인진행림상불골증검사,매개촌추취남녀각10인,진행불골증X선진단.결과 대마、온천、태평、보저4개촌수불균치분별위0.58、0.38、2.28、0.57 mg/L,기중태평촌수불균치초과국가생활음용수위생표준(1.0 mg/L).공검사8～12세인동193인,인동불반아검출솔위49.74%(96/193);공검측인동뇨양116빈,뇨불중위수위1.49 mg/L.공검사16세이상성인1503인,림상불골증검출솔위51.63%(776/1503);공대82인진행X선박편,X선불골증검출솔위20.73%(17/82),X선표현이관절퇴행성개변급골간막골화위주.결론 귀덕현인동불반아화성인림상불골증검출솔교고,불중독류행교중,방치형세각불용완.
Objective To investigate the prevalence of endemic fluorosis in Guide county of Qinghai province, in order to provide appropriate measures to monitor and control the disease. Methods Damo, Wenquan, Baoning villages(water source has been changed) and Taiping village(water source has not been changed) in Guide county were involved in the study in 2008. One tap water sample was collected in dry and rainy seasons, respectively. Water fluoride was tested in accordance with the "Standard Test Methods for Drinking Water" (GB/T 5750.5-2006); of all the children aged 8 to 12, dental fluorosis was diagnosed using Dean criteria; 6 copies of urine samples were collected in each age group, urinary fluoride was measured using fluoride ion-selective electrode (WS/T 89-1996). According to the "Clinical Diagnostic Criteria of Endemic Skeletal Fluorosis "(WS 192-2008), clinical skeletal fluorosis was determined in adults over the age of 16 by X-ray examination for 10 people in each selected village. Results The mean water fluoride was 0.58,0.38,2.28,0.37 mg/L in Damo, Wenquan, Taiping, and Baoning villages, respectively, and that of Taiping village exceeded the national standard(1.0 mg/L). One hundred and ninety-three children aged 8-12 were checked, the detection rate of dental fluorosis was 49.74% (96/193); urine samples of 116 children were tested, median urinary fluoride was 1.49 mg/L A total of 1503 adults over the age of 16 were examined, the clinical detection of skeletal fluorosis was 51.63%(776/1503); a total of 82 people were X-rayed, X-ray detection of skeletal fluorosis was 20.73%(17/82). The characteristic of X-rays were degeneration and ossification of interosseous membrane. Conclusions Prevalence of dental fluorosis of children and adult clinical skeletal fluorosis are higher. The endemic fluorosis is still comparatively serious. Prevention efforts need to be further strengthened.