中华行为医学与脑科学杂志
中華行為醫學與腦科學雜誌
중화행위의학여뇌과학잡지
CHINESE JOURNAL OF BEHAVIORAL MEDICINE AND BRAIN SCIENCE
2010年
4期
358-360
,共3页
胡细灰%周曙%余伟雄%吴燕%朱敏真
鬍細灰%週曙%餘偉雄%吳燕%硃敏真
호세회%주서%여위웅%오연%주민진
时序记忆%近事判断任务%事件相关电位
時序記憶%近事判斷任務%事件相關電位
시서기억%근사판단임무%사건상관전위
Temporal order memory%Recency judgment task%Event-related potentials(ERP)
目的 利用事件相关电位(event-related potentials,ERe)时空模式探讨时序记忆信息检索的神经机制.方法 17名青年学生参与实验.基于Sternberg范式,在编码维持期系列旱现四个不同颜色的项目一圆形;在记忆检索期,被试针对呈现的一对探针图形、须分别完成项目时序判断(时序包含三种间隔)、新旧项目再认判断及几何图形辨别三种任务.应用单因素三水平重复测量方差分析和配对比较,分析了记忆检索期的行为绩效和19通道ERe.结果 时序间隔因素的行为绩效差异有显著性:反应时间分别为(745.5±106.1)ms,(711.7±102.2)ms,(653.7±81.5)ms;(F_((1.28,20.48))=43.37,P=0.00).正确率分别为(62.8±7.0)%,(72.5±5.4)%,(84.5±6.4)%;F_((2,32))=132.60,P=0.00.项目间隔越近,反应时间越长,正确率越低.任务因素行为绩效亦显著:反应时间[F_((1.32,21.11))=135.99,P:0.00]及正确率[F_((2,32))=200.31,P=0.00],但时序记忆组与项目再认组的行为绩效差异无显著性.ERP统计参数映射提示时序记忆间隔效应起始于左颞(260～270 ms)和双侧顶枕区(280～290 ms),突出呈现在双侧顶叶(300～400 ms);时序记忆与再认记忆均涉及双侧半球的广泛区域,但两者比较未见ERP效应.结论 在时序记忆榆索阶段,时序间隔的距离效应的神经相关主要存在于双侧顶叶;时序信息的检索同客体信息一样,涉及双侧半球的广泛区域.
目的 利用事件相關電位(event-related potentials,ERe)時空模式探討時序記憶信息檢索的神經機製.方法 17名青年學生參與實驗.基于Sternberg範式,在編碼維持期繫列旱現四箇不同顏色的項目一圓形;在記憶檢索期,被試針對呈現的一對探針圖形、鬚分彆完成項目時序判斷(時序包含三種間隔)、新舊項目再認判斷及幾何圖形辨彆三種任務.應用單因素三水平重複測量方差分析和配對比較,分析瞭記憶檢索期的行為績效和19通道ERe.結果 時序間隔因素的行為績效差異有顯著性:反應時間分彆為(745.5±106.1)ms,(711.7±102.2)ms,(653.7±81.5)ms;(F_((1.28,20.48))=43.37,P=0.00).正確率分彆為(62.8±7.0)%,(72.5±5.4)%,(84.5±6.4)%;F_((2,32))=132.60,P=0.00.項目間隔越近,反應時間越長,正確率越低.任務因素行為績效亦顯著:反應時間[F_((1.32,21.11))=135.99,P:0.00]及正確率[F_((2,32))=200.31,P=0.00],但時序記憶組與項目再認組的行為績效差異無顯著性.ERP統計參數映射提示時序記憶間隔效應起始于左顳(260～270 ms)和雙側頂枕區(280～290 ms),突齣呈現在雙側頂葉(300～400 ms);時序記憶與再認記憶均涉及雙側半毬的廣汎區域,但兩者比較未見ERP效應.結論 在時序記憶榆索階段,時序間隔的距離效應的神經相關主要存在于雙側頂葉;時序信息的檢索同客體信息一樣,涉及雙側半毬的廣汎區域.
목적 이용사건상관전위(event-related potentials,ERe)시공모식탐토시서기억신식검색적신경궤제.방법 17명청년학생삼여실험.기우Sternberg범식,재편마유지기계렬한현사개불동안색적항목일원형;재기억검색기,피시침대정현적일대탐침도형、수분별완성항목시서판단(시서포함삼충간격)、신구항목재인판단급궤하도형변별삼충임무.응용단인소삼수평중복측량방차분석화배대비교,분석료기억검색기적행위적효화19통도ERe.결과 시서간격인소적행위적효차이유현저성:반응시간분별위(745.5±106.1)ms,(711.7±102.2)ms,(653.7±81.5)ms;(F_((1.28,20.48))=43.37,P=0.00).정학솔분별위(62.8±7.0)%,(72.5±5.4)%,(84.5±6.4)%;F_((2,32))=132.60,P=0.00.항목간격월근,반응시간월장,정학솔월저.임무인소행위적효역현저:반응시간[F_((1.32,21.11))=135.99,P:0.00]급정학솔[F_((2,32))=200.31,P=0.00],단시서기억조여항목재인조적행위적효차이무현저성.ERP통계삼수영사제시시서기억간격효응기시우좌섭(260～270 ms)화쌍측정침구(280～290 ms),돌출정현재쌍측정협(300～400 ms);시서기억여재인기억균섭급쌍측반구적엄범구역,단량자비교미견ERP효응.결론 재시서기억유색계단,시서간격적거리효응적신경상관주요존재우쌍측정협;시서신식적검색동객체신식일양,섭급쌍측반구적엄범구역.
Objective To investigate neural correlates of the retrieval of temporal order.Methods ERP of 19 channels was recorded from 17 healthy young students while they performed a recency judgment task,a recognition task and a visual discrimination task separately,which were based on Sternberg paradigm.One-way ANOVA of repeated-measurement and post-hoc paired comparisons were carried out for both the task factor(temporal order,recognition and control)and the temporal distance factor correspondingly.The latter contains 3 intervals (1,2 and 3)between the targets.Results The temporal distance effect was significant:the closer targets correspond to longer reaction time((745.5±106.1)ms,(711.7±102.2)ms,(653.7±81.5)ms;F_((1.28,20.48))=43.37,P=0.00]and higher error rate((62.8±7.0)%,(72.5±5.4)%,(84.5±6.4)%;F_((1.32,21.11))=135.99,P=0.00].Significant behavioral effect of the task factor was also found for both reaction time(F_((1.32,21.11))=135.99,P=0.00)and error rate(F_((2,32))=200.31,P=0.00).No significant behavioral difference was found between the temporal order group and the recognition group.The spatiotemporal pattern of statistical parametric mapping(SPM)suggested the ERP effects of temporal order were presented in left temporal region (260～270 ms),bilateral parietal-occipital areas(280～290 ms),and bilateral parietal lobes(300～400 ms)prominently.No ERP effect was found between the temporal order task and the recognition task.Conclusions The neural correlates of the temporal distance effect exist in bilateral parietal regions.Temporal order as well as object information processing involves similar cerebral regions during the retrieval period.
