中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2012年
6期
6-7
,共2页
王东伟%刘敏%孙广信%王全河%纪焕文%张晓君
王東偉%劉敏%孫廣信%王全河%紀煥文%張曉君
왕동위%류민%손엄신%왕전하%기환문%장효군
缺血性心力衰竭%曲美他嗪%美托洛尔缓释片%心室利钠多肽
缺血性心力衰竭%麯美他嗪%美託洛爾緩釋片%心室利鈉多肽
결혈성심력쇠갈%곡미타진%미탁락이완석편%심실리납다태
Ischemic heart failure%Trimetazidine%Metoprolol succinate sustained-release tablets%B-type natriuretic peptide
目的 观察曲美他嗪片和美托洛尔缓释片联合治疗对缺血性心力衰竭患者左室收缩功能及血浆心室利钠多肽(BNP)水平的影响.方法 将102例缺血性心力衰竭患者随机分为常规治疗组及联合治疗组,分别于治疗前及治疗后6个月测定左室射血分数、6 min步行试验及血浆BNP、C-反应蛋白(CRP)水平.结果 联合治疗组较常规治疗组心室功能及活动耐量均明显改善,BNP及CRP显著降低(P＜0.01).结论 曲美他嗪和美托洛尔缓释片联用能有效改善缺血性心肌病患者心室功能及活动耐量,提高生活质量.
目的 觀察麯美他嗪片和美託洛爾緩釋片聯閤治療對缺血性心力衰竭患者左室收縮功能及血漿心室利鈉多肽(BNP)水平的影響.方法 將102例缺血性心力衰竭患者隨機分為常規治療組及聯閤治療組,分彆于治療前及治療後6箇月測定左室射血分數、6 min步行試驗及血漿BNP、C-反應蛋白(CRP)水平.結果 聯閤治療組較常規治療組心室功能及活動耐量均明顯改善,BNP及CRP顯著降低(P＜0.01).結論 麯美他嗪和美託洛爾緩釋片聯用能有效改善缺血性心肌病患者心室功能及活動耐量,提高生活質量.
목적 관찰곡미타진편화미탁락이완석편연합치료대결혈성심력쇠갈환자좌실수축공능급혈장심실리납다태(BNP)수평적영향.방법 장102례결혈성심력쇠갈환자수궤분위상규치료조급연합치료조,분별우치료전급치료후6개월측정좌실사혈분수、6 min보행시험급혈장BNP、C-반응단백(CRP)수평.결과 연합치료조교상규치료조심실공능급활동내량균명현개선,BNP급CRP현저강저(P＜0.01).결론 곡미타진화미탁락이완석편련용능유효개선결혈성심기병환자심실공능급활동내량,제고생활질량.
Objective To observe the effect of trimetazidine tablets combined with metoprolol succinate sustained-release tablets on left ventricular systolic function and serum B-type natriuretic peptide(BNP) level in patients with ischemic heart failure(IHF).Methods A total of 102 patients with IHF were randomly divided into two groups (conventional treatment group and combined treatment group).The levels of serum BNP,CRP,left ventricular ejection fraction(LVEF) and 6 minutes walk test were measured before treatment and 6 months after treatment.Results Ventricular function and exercise tolerance improved obviously,and serum BNP and CRP levels reduced remarkably in combined treatment group than that in conventional treatment group ( P ＜ 0.01 ).Conclusions Trimentazidine combined with metoprolol succinate sustained-release tablets can effectively improve ventricular function and exercise tolerance,and improve the life quality of patients with IHF.
