CAJ | 학술논문

冠状动脉粥样硬化性心脏病危险因素、血管造影下冠状动脉病变特征、支架置入操作技术参数是影响冠状动脉病变支架置入后再狭窄的主要危险因子.这些危险因子在不同的组合条件下可对支架置入后再狭窄产生不同的影响.目前研究结果较一致的可增加支架置入后再狭窄危险的因素为:冠状动脉病变长度、病变血管直径<3 mm、开口病变、支架总长度以及置入支架的个数.同样研究结果较一致的足:药物洗脱支架(紫杉醇药物洗脱支架和雷帕霉素药物洗脱支架)与裸金属支架相比,明显降低了发生支架置入后再狭窄的危险;而这2种药物洗脱支架之间相比,雷帕霉素药物洗脱支架在降低支架置入后再狭窄风险方面似乎优于紫杉醇药物沈脱支架.而其他的一些危险因素,如年龄、性别、吸烟、高血压等目前的研究结果并不一致.
관상동맥죽양경화성심장병위험인소、혈관조영하관상동맥병변특정、지가치입조작기술삼수시영향관상동맥병변지가치입후재협착적주요위험인자.저사위험인자재불동적조합조건하가대지가치입후재협착산생불동적영향.목전연구결과교일치적가증가지가치입후재협착위험적인소위:관상동맥병변장도、병변혈관직경<3 mm、개구병변、지가총장도이급치입지가적개수.동양연구결과교일치적족:약물세탈지가(자삼순약물세탈지가화뢰파매소약물세탈지가)여라금속지가상비,명현강저료발생지가치입후재협착적위험;이저2충약물세탈지가지간상비,뢰파매소약물세탈지가재강저지가치입후재협착풍험방면사호우우자삼순약물침탈지가.이기타적일사위험인소,여년령、성별、흡연、고혈압등목전적연구결과병불일치.
The risk factors of coronary artery disease, angiographic and procedural features are the main risk factors of restenosis after coronary artery stent implantation. In different combinations, these risk factors have different effects on coronary restenosis. The risk factors that the results of trials were more consistent include coronary lesion length, lesion vessel diameter <3 mm, ostial disease, total stent length, and number of stent. The same results of trials as stated above indicated that drug-eluting stent (sirolimus-eluting stent and paclitaxel-eluting stent), compared with bare-metal stent, significantly decreased the risk of restenosis. Compared these two drug-eluting stent, sirolimus-eluting stent was superior to paclitaxel-eluting stent on lowering the risk of restenosis. About other risk factors, e.g. age, sex, smoking, hypertension, the results of trials had inconsistent.