中国医学科学院学报
中國醫學科學院學報
중국의학과학원학보
ACTA ACADEMIAE MEDICINAE SINICAE
2009年
5期
644-650
,共7页
阿司匹林%阿司匹林抵抗
阿司匹林%阿司匹林牴抗
아사필림%아사필림저항
aspirin%aspirin resistance
阿司匹林是抗血栓治疗的重要药物,阿司匹林抵抗是影响其疗效的常见原因.阿司匹林抵抗目前主要指实验室阿司匹林抵抗,可通过血栓素A_2测定,依赖血栓素的血小板功能试验来诊断.多项临床试验证实,实验室阿司匹林抵抗和临床血管事件相关.
阿司匹林是抗血栓治療的重要藥物,阿司匹林牴抗是影響其療效的常見原因.阿司匹林牴抗目前主要指實驗室阿司匹林牴抗,可通過血栓素A_2測定,依賴血栓素的血小闆功能試驗來診斷.多項臨床試驗證實,實驗室阿司匹林牴抗和臨床血管事件相關.
아사필림시항혈전치료적중요약물,아사필림저항시영향기료효적상견원인.아사필림저항목전주요지실험실아사필림저항,가통과혈전소A_2측정,의뢰혈전소적혈소판공능시험래진단.다항림상시험증실,실험실아사필림저항화림상혈관사건상관.
Aspirin is an important antithrombotic agent However, its clinical benefit is impaired by aspirin resistance.The term of "aspirin resistance" usually refers to laboratory resistance.It can be identified by measuring thromboxane A_2 or thromboxane-dependent platelet function.Clinical trials have shown that laboratory aspirin resistance is correlated with vascular events.