CAJ | 학술논문

目的:评价血液透析患者感染丙型肝炎病毒(HCV)的阳转率和危险因素.方法:随访1998年6月~2010年6月在本院透析的血透患者,共纳入2 465例血透患者,采用ELISA法每隔6月在同一实验室检测抗-HCV.结果:1998年6月的抗HCV阳性率为54.7%,每隔半年的阳性率分别为54.7%,53.8%,52.6%,53.0 %,51.2%,45.9%,45.5%,48.2%,35.6%,33.7%,33.7%,31.7%,30.4%,28.4%,27.2%,24.5%,20.8%,19.4%,16.6%,14.4%,15.3%,15.2%,12.5%,11.9%和10.0%.在1~150个月随访期间,总计238例患者阳转,随访1~12月者阳转率为4.5%,13~24月者为6.9%,25~48月者为11.9%,49~60月者 28.1%,61~72月者 35.1%,73~84月者38.6%,85~96月者阳转率46.9%,97~108月者 56.3%,109~126月者 63.6%,随访至139~150 月时,阳转率已高达75%.结论:提示透析环境对HCV传播有影响,可能一方面通过共用透析机,一方面是由于未隔离阳性患者;严格的消毒隔离措施对降低HCV感染和阳转有重要作用.
목적:평개혈액투석환자감염병형간염병독(HCV)적양전솔화위험인소.방법:수방1998년6월~2010년6월재본원투석적혈투환자,공납입2 465례혈투환자,채용ELISA법매격6월재동일실험실검측항-HCV.결과:1998년6월적항HCV양성솔위54.7%,매격반년적양성솔분별위54.7%,53.8%,52.6%,53.0 %,51.2%,45.9%,45.5%,48.2%,35.6%,33.7%,33.7%,31.7%,30.4%,28.4%,27.2%,24.5%,20.8%,19.4%,16.6%,14.4%,15.3%,15.2%,12.5%,11.9%화10.0%.재1~150개월수방기간,총계238례환자양전,수방1~12월자양전솔위4.5%,13~24월자위6.9%,25~48월자위11.9%,49~60월자 28.1%,61~72월자 35.1%,73~84월자38.6%,85~96월자양전솔46.9%,97~108월자 56.3%,109~126월자 63.6%,수방지139~150 월시,양전솔이고체75%.결론:제시투석배경대HCV전파유영향,가능일방면통과공용투석궤,일방면시유우미격리양성환자;엄격적소독격리조시대강저HCV감염화양전유중요작용.