中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2011年
35期
26-28
,共3页
肝肿瘤%肝性脑病%介入
肝腫瘤%肝性腦病%介入
간종류%간성뇌병%개입
Liver neoplasms%Hepatic encephalopathy%Intervention
目的 探讨原发性肝癌(PLC)介入治疗后并发肝性脑病(HE)的相关危险因素.方法 行介入治疗的PLC患者93例,根据治疗效果分为好转组(32例)和恶化组(61例).对两组患者年龄、性别、家族史、Child-Pugh分级、HE分期、肝癌分型、肝外转移、肝癌合并症以及腹腔淋巴结转移等22项PLC介入治疗后并发HE的相关因素进行统计学分析.结果 肝癌合并症≥3个、肝癌合并肝硬化、凝血酶原时间、尿素氮、胆碱酯酶、Child-Pugh分级C级、HE分期Ⅲ～Ⅳ期为影响PLC介入治疗后并发HE的预后相关因素,Logistic多因素回归分析表明,肝癌合并症≥3个、Child-Pugh分级C级、HE分期Ⅲ～Ⅳ期为影响PLC介入治疗后并发HE预后的独立危险因素.结论 肝癌合并症≥3个、Child-Pugh分级C级、HE分期Ⅲ～Ⅳ期可以作为评价PLC介入治疗后并发HE预后的标准.
目的 探討原髮性肝癌(PLC)介入治療後併髮肝性腦病(HE)的相關危險因素.方法 行介入治療的PLC患者93例,根據治療效果分為好轉組(32例)和噁化組(61例).對兩組患者年齡、性彆、傢族史、Child-Pugh分級、HE分期、肝癌分型、肝外轉移、肝癌閤併癥以及腹腔淋巴結轉移等22項PLC介入治療後併髮HE的相關因素進行統計學分析.結果 肝癌閤併癥≥3箇、肝癌閤併肝硬化、凝血酶原時間、尿素氮、膽堿酯酶、Child-Pugh分級C級、HE分期Ⅲ～Ⅳ期為影響PLC介入治療後併髮HE的預後相關因素,Logistic多因素迴歸分析錶明,肝癌閤併癥≥3箇、Child-Pugh分級C級、HE分期Ⅲ～Ⅳ期為影響PLC介入治療後併髮HE預後的獨立危險因素.結論 肝癌閤併癥≥3箇、Child-Pugh分級C級、HE分期Ⅲ～Ⅳ期可以作為評價PLC介入治療後併髮HE預後的標準.
목적 탐토원발성간암(PLC)개입치료후병발간성뇌병(HE)적상관위험인소.방법 행개입치료적PLC환자93례,근거치료효과분위호전조(32례)화악화조(61례).대량조환자년령、성별、가족사、Child-Pugh분급、HE분기、간암분형、간외전이、간암합병증이급복강림파결전이등22항PLC개입치료후병발HE적상관인소진행통계학분석.결과 간암합병증≥3개、간암합병간경화、응혈매원시간、뇨소담、담감지매、Child-Pugh분급C급、HE분기Ⅲ～Ⅳ기위영향PLC개입치료후병발HE적예후상관인소,Logistic다인소회귀분석표명,간암합병증≥3개、Child-Pugh분급C급、HE분기Ⅲ～Ⅳ기위영향PLC개입치료후병발HE예후적독립위험인소.결론 간암합병증≥3개、Child-Pugh분급C급、HE분기Ⅲ～Ⅳ기가이작위평개PLC개입치료후병발HE예후적표준.
Objective To explore the related risk factors of hepatic encephalopathy (HE) after the primary liver cancer interventional treatment.Methods Ninety-three cases with primary liver cancer who were treated with interventional treatment were chosen.According to the result,all patients were divided into two groups,improving group (32 cases) and worsen group (61 cases).Collected the patient's age,gender,family history,Child-Pugh classification,HE staging,liver cancer subtypes,extrahepatic transfer,liver cancer complications and lymph node metastases and other items,for all 22 items,and the results for statistical analysis.Results Complications more than 3,liver cancer combined with liver cirrhosis,prothrombin time,urea nitrogen,cholinesterase,Child-Pugh grading grade C,HE staging Ⅲ -Ⅳperiod were related factors for HE prognosis.Logistic regression analysis results showed that complications more than 3,Child-Pugh grading grade C,HE staging Ⅲ -Ⅳ period were independent risk factors for HE prognosis.Conclusions Complications more than 3,Child-Pugh grading grade C,HE staging Ⅲ- Ⅳ period were independent risk factors for HE prognosis.It can be used as evaluation standard for HE after the primary liver cancer interventional treatment.
