CAJ | 학술논문

目的了解入伍新兵人群中流行性脑脊髓膜炎(流脑)IgG抗体的流行分布情况,为今后预防提供科学依据.方法采用血清流行病学调查方法,用ELISA法对北京军区近4年来自7个省市的360名入伍新兵的血清进行流脑IgG抗体检测,统计分析其阳性率.结果各年间入伍新兵血清流脑IgG抗体历年无显著变化,阳性率在66.67%～96.67%,平均83.33%;抗体含量在6.23～26.47μg/mL,平均12.42μg/mL,地区间差异有统计学意义,湖北省(96.67%)、山东省(91.43%)和北京市(88.00%)较高,河南省(66.67%)和陕西省(72.50%)较低;入伍前工作与否人群,抗体阳性检出率差异无统计学意义(χ2=0.12,P>0.05).结论入伍新兵人群中流脑IgG抗体阳性率为66.67%～96.67%,抗体含量在6.23～26.47 μg/mL,并有地区差异,所以在新兵入伍期间应采取预防接种、健康教育等有效预防措施.
목적 료해입오신병인군중류행성뇌척수막염(류뇌)IgG항체적류행분포정황,위금후예방제공과학의거.방법 채용혈청류행병학조사방법,용ELISA법대북경군구근4년래자7개성시적360명입오신병적혈청진행류뇌IgG항체검측,통계분석기양성솔.결과 각년간입오신병혈청류뇌IgG항체력년무현저변화,양성솔재66.67%～96.67%,평균83.33%;항체함량재6.23～26.47μg/mL,평균12.42μg/mL,지구간차이유통계학의의,호북성(96.67%)、산동성(91.43%)화북경시(88.00%)교고,하남성(66.67%)화합서성(72.50%)교저;입오전공작여부인군,항체양성검출솔차이무통계학의의(χ2=0.12,P>0.05).결론 입오신병인군중류뇌IgG항체양성솔위66.67%～96.67%,항체함량재6.23～26.47 μg/mL,병유지구차이,소이재신병입오기간응채취예방접충、건강교육등유효예방조시.
Objective To investigate the distribution of serogroup A epidemic cerebrospinal meningitis antibody IgG in recruits, provide scientific evidence for further prevention and control of the disease. Methods By using ELISA, serogroup A epidemic cerebrospinal meningitis antibody IgG serum samples of 360 recruits, who came from 7 provinces during the past four years, were detected, and the positive rate was analysed. Results There was no statistical difference in serum serogroup A epidemic cerebrospinal meningitis antibody IgG levels in each years, which ranged from 66.67% to 96.67% with a average rate of 83.33%, content of antibody ranged from 6.23 μg/mL to 26.47 μg/mL with an average content of 12.42 μg/mL, regional difference existed. The higher level found in recruits from Hubei (96.67%) 、Shandong (91.43%)and Beijing (88.00%), and lower level from Henan (66.67%) and Shaanxi(72.50%). There was no significant correlation between the antibody IgG positive rate and education or occupation background of the recruits before their recruitment (χ2 = 0.12, P > 0.05). Conclusions The positive rate of serogroup A epidemic cerebrospinal meningitis antibody IgG in recruits range from 66.67% to 96.67%, antibody level range from 6.23 μg/mL to 26.47 μg/mL, with a average content of 12.42 (μg/mL. The positive rate for antibody IgG varies in different provinces. It is necessary to give vaccination and education for the recruits to prevent serogroup A epidemic cerebrospinal meningitis spreading.