CAJ | 학술논문

允许性高碳酸血症是肺保护性通气策略的被动结果.早期认为动脉血二氧化碳分压升高及由之引起的酸中毒会导致心血管恶性事件发生率增高.而近期的研究结果显示高碳酸血症本身对脏器有保护作用,从而引入了治疗性高碳酸血症的概念.高碳酸血症可显著影响呼吸循环功能.该文从高碳酸血症对血管张力、肺泡通透性的影响等几个方面作一综述.
윤허성고탄산혈증시폐보호성통기책략적피동결과.조기인위동맥혈이양화탄분압승고급유지인기적산중독회도치심혈관악성사건발생솔증고.이근기적연구결과현시고탄산혈증본신대장기유보호작용,종이인입료치료성고탄산혈증적개념.고탄산혈증가현저영향호흡순배공능.해문종고탄산혈증대혈관장력、폐포통투성적영향등궤개방면작일종술.
Permissive hypercapnia is a passive result of lung protective ventilation strategy. Earlier studies thought that increased arterial carbon dioxide pressure and acidosis caused by it could lead to increased incidence of cardiovascular vicious events. But recent studies have shown that hypercapnia has a protective effect on organs,thereby the concept of therapeutic hypercapnia is introduced. Hypercapnia can significantly affect respiratory circulatory functions. This article reviews the effects of hypercapnia on vascular tone,alveolar permeability.