CAJ | 학술논문

目的了解新疆维吾尔族人群代谢综合征(MS)患病情况,比较美国国家胆固醇教育计划成人治疗组第三次报告(ATPⅢ)、国际糖尿病联盟(IDF)和中华医学会糖尿病学分会(CDS)建议的MS诊断标准在维吾尔族人群中应用的差异.方法对新疆地区2053名维吾尔族30～80岁居民进行横断面调查,根据3种诊断标准分别计算MS患病率,分析不同诊断标准下MS异常组分及危险因素聚集的检出情况,比较3种诊断标准在维吾尔族人群中的一致性.结果 (1)3种诊断标准患病率(标化患病率)分别为35.80%(29.64%)、39.4l%(35.88%)和23.72%(19.17%);(2)3种标准对MS患者3个以上危险因素聚集的检出率分别为98.64%、97.90%和92.81%;(3)3种诊断标准在维吾尔族人群中应用的一致性两两比较,ATPⅢ标准与IDF标准的一致性较好(一致率为0.9026,Youdcn指数为0.7928,Kappa值为0.7801),CDS标准与另外两种标准(ATPⅢ和IDF)的一致性不高.结论在新疆维吾尔族人群中应用3种MS诊断标准,获得的患病率、危险组分聚集情况和一致性差异较大,IDF标准检出率最高,ATPⅢ标准对危险因素聚集检出率最高,且两者一致性较好,优于CDS标准.
목적 료해신강유오이족인군대사종합정(MS)환병정황,비교미국국가담고순교육계화성인치료조제삼차보고(ATPⅢ)、국제당뇨병련맹(IDF)화중화의학회당뇨병학분회(CDS)건의적MS진단표준재유오이족인군중응용적차이.방법 대신강지구2053명유오이족30～80세거민진행횡단면조사,근거3충진단표준분별계산MS환병솔,분석불동진단표준하MS이상조분급위험인소취집적검출정황,비교3충진단표준재유오이족인군중적일치성.결과 (1)3충진단표준환병솔(표화환병솔)분별위35.80%(29.64%)、39.4l%(35.88%)화23.72%(19.17%);(2)3충표준대MS환자3개이상위험인소취집적검출솔분별위98.64%、97.90%화92.81%;(3)3충진단표준재유오이족인군중응용적일치성량량비교,ATPⅢ표준여IDF표준적일치성교호(일치솔위0.9026,Youdcn지수위0.7928,Kappa치위0.7801),CDS표준여령외량충표준(ATPⅢ화IDF)적일치성불고.결론 재신강유오이족인군중응용3충MS진단표준,획득적환병솔、위험조분취집정황화일치성차이교대,IDF표준검출솔최고,ATPⅢ표준대위험인소취집검출솔최고,차량자일치성교호,우우CDS표준.
Objective To investigate the prevalence of metabolic syndrome (MS) among Xinjiang Uigur population aged 30-80 and to compare the differences of the three diagnostic criteria used for MS. The three diagnostic criteria were developed by the National Cholesterol Education Program (ATP Ⅲ), International Diabetes Federation (IDF) and Chinese Medical Association Diabetes Branch (CDS). Methods A cross-sectional study was conducted on 2053 Xinjiang Uigur people aged 30-80. The prevalence of MS and the degree of agreement were both calculated according to the three definitions. The results of MS components were also analyzed. Results (1) According to the three definitions (ATP Ⅲ, IDF and CDS), thc prevalence and adjusted prevalence rates of MS were 35.80% (29.64%), 39.41% (35.88%) and 23.72% (19.17%). (2)According to the three definitions (the ATP Ⅲ , IDF and CDS), the prevalence rates of subjects who had at least 3 risk factors were 98.64%, 97.90% and 92.81%. (3) Among all the subjects with MS, the MS diagnostic criteria of ATP Ⅲ and IDF were in good accordance with the Kappa index (0.7801), Youden index (0.7928) and the concordance rate (0.9026). CDS was in relatively weak agreement when comparing with other definitions (ATP Ⅲ and IDF). Conclusion Our findings revealed big differences regarding the prevalence rates, the degree of agreement and the aggregation of risk components on MS among Xinjiang Uigur population. The detection rate of IDF criteria on MS and the highest while detection rate of ATP Ⅲ criteria on subjects presented at least 3 risk factors were the highest. The concordance of ATP Ⅲ criteria and IDF seemed to be a better one.