国际医学寄生虫病杂志
國際醫學寄生蟲病雜誌
국제의학기생충병잡지
INTERNATIONAL JOURNAL OF MEDICAL PARASITIC DISEASES
2011年
3期
170-172
,共3页
许慧%崔京涛%倪安平%吴叶丽
許慧%崔京濤%倪安平%吳葉麗
허혜%최경도%예안평%오협려
弓形虫%阳性率%酶联免疫吸附试验
弓形蟲%暘性率%酶聯免疫吸附試驗
궁형충%양성솔%매련면역흡부시험
Toxoplasma gondii%Positive rate%Enzyme-linked immunosorbent assay
目的 了解北京协和医院住院患者弓形虫感染的情况.方法 收集2008-2010年期间北京协和医院住院和门诊患者的血样,用酶联免疫吸附试验(ELISA)检测血清抗弓形虫IgG抗体,计算住院患者血清弓形虫抗体的阳性率,并按科室和疾病分别统计分析患者弓形虫抗体的阳性率.结果 住院组和门诊组患者的弓形虫抗体阳性率分别为2.22%、1.01%,住院组男性、女性弓形虫抗体阳性率分别为1.79%、2.46%,门诊组男性、女性弓形虫抗体阳性率分别为0.83%、1.13%,住院组与对照组相比差异均有统计学意义(P<0.01).免疫科、心内科、重症医学科、普通内科、神经内科、泌尿外科及急诊科的弓形虫抗体阳性率依次为6.55%、5.13%、5.08%、3.72%、3.83%、2.56%、2.11%,与对照组(1.01%)相比差异均有统计学意义(P<0.05).弓形虫抗体阳性率较高的疾病有人类获得性免疫缺陷综合症(human acquired immunodeficient syndrome,AIDs)、系统性红斑狼疮(systemic lupus erythematosus,SLE)、免疫系统疾病、心脏系统疾病、流产、神经系统疾病以及不明原因发热,阳性率依次为25.00%、14.49%、9.47%、5.13%、5.06%、3.83%、3.42%.结论住院患者弓形虫抗体阳性率普遍高于对照组,提示部分住院患者为弓形虫感染的高危人群,应予以关注.
目的 瞭解北京協和醫院住院患者弓形蟲感染的情況.方法 收集2008-2010年期間北京協和醫院住院和門診患者的血樣,用酶聯免疫吸附試驗(ELISA)檢測血清抗弓形蟲IgG抗體,計算住院患者血清弓形蟲抗體的暘性率,併按科室和疾病分彆統計分析患者弓形蟲抗體的暘性率.結果 住院組和門診組患者的弓形蟲抗體暘性率分彆為2.22%、1.01%,住院組男性、女性弓形蟲抗體暘性率分彆為1.79%、2.46%,門診組男性、女性弓形蟲抗體暘性率分彆為0.83%、1.13%,住院組與對照組相比差異均有統計學意義(P<0.01).免疫科、心內科、重癥醫學科、普通內科、神經內科、泌尿外科及急診科的弓形蟲抗體暘性率依次為6.55%、5.13%、5.08%、3.72%、3.83%、2.56%、2.11%,與對照組(1.01%)相比差異均有統計學意義(P<0.05).弓形蟲抗體暘性率較高的疾病有人類穫得性免疫缺陷綜閤癥(human acquired immunodeficient syndrome,AIDs)、繫統性紅斑狼瘡(systemic lupus erythematosus,SLE)、免疫繫統疾病、心髒繫統疾病、流產、神經繫統疾病以及不明原因髮熱,暘性率依次為25.00%、14.49%、9.47%、5.13%、5.06%、3.83%、3.42%.結論住院患者弓形蟲抗體暘性率普遍高于對照組,提示部分住院患者為弓形蟲感染的高危人群,應予以關註.
목적 료해북경협화의원주원환자궁형충감염적정황.방법 수집2008-2010년기간북경협화의원주원화문진환자적혈양,용매련면역흡부시험(ELISA)검측혈청항궁형충IgG항체,계산주원환자혈청궁형충항체적양성솔,병안과실화질병분별통계분석환자궁형충항체적양성솔.결과 주원조화문진조환자적궁형충항체양성솔분별위2.22%、1.01%,주원조남성、녀성궁형충항체양성솔분별위1.79%、2.46%,문진조남성、녀성궁형충항체양성솔분별위0.83%、1.13%,주원조여대조조상비차이균유통계학의의(P<0.01).면역과、심내과、중증의학과、보통내과、신경내과、비뇨외과급급진과적궁형충항체양성솔의차위6.55%、5.13%、5.08%、3.72%、3.83%、2.56%、2.11%,여대조조(1.01%)상비차이균유통계학의의(P<0.05).궁형충항체양성솔교고적질병유인류획득성면역결함종합증(human acquired immunodeficient syndrome,AIDs)、계통성홍반랑창(systemic lupus erythematosus,SLE)、면역계통질병、심장계통질병、유산、신경계통질병이급불명원인발열,양성솔의차위25.00%、14.49%、9.47%、5.13%、5.06%、3.83%、3.42%.결론주원환자궁형충항체양성솔보편고우대조조,제시부분주원환자위궁형충감염적고위인군,응여이관주.
Objective To investigate the status of Toxoplasma gondii infection in hospitalized patients in Peking Union Medical College Hospital.Methods Samples of outpatients and inpatients during 2008-1010 were collected.Enzyme-linked immunosorbent assay(ELISA)was used to detect anti-Toxoplasma antibody IgG.The positive rate of IgG antibody of inpatients was analyzed according to the department and diseases. Results The positive rates of anti-Toxoplasma antibody of inpatients and outpatients were 2.22%and 1.01% respectively.The positive rates of male and female in-patient were 1.79%and 2.46%.The positive rates of male and female out-patient were 0.83%and 1.13%.The difference was significant between inpatients and outpatients(P<0.01).The positive rates of department of immunology,cardiology,intensive care unit (ICU),general internal medicine,neurology,urology and emergency were 6.55%,5.13%,5.08%,3.72%,3.83%,2.56%and 2.11%,respectively.It was significantly different between the experiment group and the control group(1.01%)(P<0.05).The positive mtes were higher in some diseases such as the human acquired immunodeficient syndrome(AIDS),systemic lupus erythematosus(SLE),immunologic disease,cerebrovascular disease,abortion,the disease of the nervous system and the unclear reason gives off fever with the positive rates of 25.00%,14.49%,9.47%,5.13%,5.06%,3.83%,3.42%.Conclusion The positive rate of anti-Toxoplasma antibody in hospitalized patient was higher than that in the outpatients.It indicated that much attention shoed be paid to the inpatients for the hish risk of Toxoplasma infection.
