CAJ | 학술논문

目的观察经导管动脉化疗栓塞(TACE)与经皮无水乙酸注射(PAI)联合治疗HBV感染相关性肝癌的疗效.方法收集2006年1月至2008年6月在浙江省舟山医院就诊的65例中晚期肝癌患者,按数字表法随机分为TACE与PAI联合治疗组(32例),TACE单纯治疗组(33例),对治疗的有效率及患者的生存率进行回顾性分析.结果 TACE+PAI联合治疗组有效22例,总有效率为68.75%,TACE单纯治疗组有效14例,总有效率为42.42%,两组差异具有统计学意义(x2=5.26,P＜0.05).联合治疗组治疗后1年、2年、3年的生存率分别为84.38%、62.50%和40.62%,单纯治疗组则分别为51.52%、24.24%和9.09%,差异均有统计学意义(x2=6.13、5.44、4.79,P＜0.05).结论 TACE与PAI联合治疗肝癌的效果优于TACE单纯治疗.
목적 관찰경도관동맥화료전새(TACE)여경피무수을산주사(PAI)연합치료HBV감염상관성간암적료효.방법 수집2006년1월지2008년6월재절강성주산의원취진적65례중만기간암환자,안수자표법수궤분위TACE여PAI연합치료조(32례),TACE단순치료조(33례),대치료적유효솔급환자적생존솔진행회고성분석.결과 TACE+PAI연합치료조유효22례,총유효솔위68.75%,TACE단순치료조유효14례,총유효솔위42.42%,량조차이구유통계학의의(x2=5.26,P＜0.05).연합치료조치료후1년、2년、3년적생존솔분별위84.38%、62.50%화40.62%,단순치료조칙분별위51.52%、24.24%화9.09%,차이균유통계학의의(x2=6.13、5.44、4.79,P＜0.05).결론 TACE여PAI연합치료간암적효과우우TACE단순치료.
Objective To observe the effection and survival rate of transcatheter arterial chemoembolization (TACE) combinded with percutaneous acetic acid injection(PAI)in treating primary carcinoma of liver associated with hepatitis B virus infection. Methods 65 patients in mid-advanced primary carcinoma of liver were recruited during January 2006 to June 2008. All the patients were randomly divided into two groups: combination and noncombination therapy. 32 patients were treated by TACE combined with PAI, 33 patients were treated with TACE alone. The effective rates and survival rates were analysed retrospectively. Results 22 patients in combination group were effective, total effective rate was 68.75%, while 14 cases in TACE alone group were effective, the rate was 42.42%, there was a statistical difference between the two groups(x2 = 5.26, P<0.05). The 1, 2,3 year survival rates in combination group were 84.38%,62.50% and 40.62% respectively,while in TACE alone group were 51.52%,24.24% and 9.09%, there were also statistical differences between the two groups (x2 = 6.13,5.44, 4.79, P < 0.05). Conclusions TACE combined with PAI therapy is more effective than TACE alone in treating HCC.