CAJ | 학술논문

目的探讨胃肠道类癌的诊断治疗和预后影响因素.方法对1998年12月至2007年12月间收治的40例胃肠道类癌患者的临床资料进行回顾性分析.结果 40例患者男女比例1.86∶1,平均年龄59.3岁.主要临床表现为腹部疼痛、消化道出血和腹泻.病灶中位大小4 cm,肿瘤直径≤2 cm者5年生存率88%,直径>2 cm者5年生存率为32%(P=0.0038).T1-2、T3和T4期患者的5年生存率具有明显差异(P<0.01),分别为82%、44%和17%.不伴有淋巴结转移者和伴有淋巴结转移者的5年生存率分别为80%和31%(P=0.0017),总5年生存率52%.结论手术是胃肠道类癌的主要治疗手段,预后和肿瘤大小、浸润深度以及淋巴结转移相关.
목적 탐토위장도유암적진단치료화예후영향인소.방법 대1998년12월지2007년12월간수치적40례위장도유암환자적림상자료진행회고성분석.결과 40례환자남녀비례1.86∶1,평균년령59.3세.주요림상표현위복부동통、소화도출혈화복사.병조중위대소4 cm,종류직경≤2 cm자5년생존솔88%,직경>2 cm자5년생존솔위32%(P=0.0038).T1-2、T3화T4기환자적5년생존솔구유명현차이(P<0.01),분별위82%、44%화17%.불반유림파결전이자화반유림파결전이자적5년생존솔분별위80%화31%(P=0.0017),총5년생존솔52%.결론 수술시위장도유암적주요치료수단,예후화종류대소、침윤심도이급림파결전이상관.
Objective To explore the diagnosis and management of gastrointestinal careinoid tumors and ana-lyze its prognostic factor.Methods Clinical data of 40 patients with gastrointestinal carcinoid tumors were retrospec-tively analyzed from Dec.1998 to Dec.2007.Results The average age of the patients was 59.3 years old,with male to female ratio of 1.86:1.The major symptoms included upper abdominal pain,gut bleeding and diarrhea.The average diameter of the tumors Was 4cm.The 5-year survival rate of patients with tumor size ≤2 cm was 88%.which was sig-nificantly higher than that(32%)for those with tumor size >2 cm in size(P=0.0038).The 5-year survival rate of the patients with T1-2,T3 and T4 Wag 82%,44% and 17%(P<0.01),respectively.For the patients without lymph node metastasis,their 5-years survival rate Was 80%,and the rate of those with lymph node metastasis was only 31%(P=0.0017).The overall 5-year survival rate of the 40 cases was 52%.Conclusions Radical resection is the pri-mary treatment for gastrointestinal earcinoid tumors.The prognosis of gastrointestinal carcinoid tumors is correlated to the size of tumor,depth of invasion and lymph node metastasis.