中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2012年
4期
495-496
,共2页
腹腔镜%促性腺素释放激素类似物%子宫内膜异位症
腹腔鏡%促性腺素釋放激素類似物%子宮內膜異位癥
복강경%촉성선소석방격소유사물%자궁내막이위증
Laparoscope%GnRH-α%Endometriosis
目的 探讨腹腔镜术后联合应用促性腺素释放激素类似物(GnRH-α)治疗子宫内膜异位症的临床疗效.方法 将接受腹腔镜手术治疗后的子宫内膜异位症患者185例随机分为两组,观察组与对照组分别接受GnRH-α(93例)和孕三烯酮(92例)治疗,服药后随访24个月,比较两组术后盆腔症状改善、复发及妊娠情况.结果 观察组治疗后盆腔症状改善率为87.1％、妊娠率为79.3％,高于对照组的70.7％、52.4％(x2 =7.517,4.059,均P＜0.05),观察组复发率为19.4％,低于对照组的34.8％(x2=5.581,P＜0.05).结论 腹腔镜术后联合使用GnRH-α治疗子宫内膜异位症可有效改善患者的盆腔症状、减少复发和提高妊娠率.
目的 探討腹腔鏡術後聯閤應用促性腺素釋放激素類似物(GnRH-α)治療子宮內膜異位癥的臨床療效.方法 將接受腹腔鏡手術治療後的子宮內膜異位癥患者185例隨機分為兩組,觀察組與對照組分彆接受GnRH-α(93例)和孕三烯酮(92例)治療,服藥後隨訪24箇月,比較兩組術後盆腔癥狀改善、複髮及妊娠情況.結果 觀察組治療後盆腔癥狀改善率為87.1％、妊娠率為79.3％,高于對照組的70.7％、52.4％(x2 =7.517,4.059,均P＜0.05),觀察組複髮率為19.4％,低于對照組的34.8％(x2=5.581,P＜0.05).結論 腹腔鏡術後聯閤使用GnRH-α治療子宮內膜異位癥可有效改善患者的盆腔癥狀、減少複髮和提高妊娠率.
목적 탐토복강경술후연합응용촉성선소석방격소유사물(GnRH-α)치료자궁내막이위증적림상료효.방법 장접수복강경수술치료후적자궁내막이위증환자185례수궤분위량조,관찰조여대조조분별접수GnRH-α(93례)화잉삼희동(92례)치료,복약후수방24개월,비교량조술후분강증상개선、복발급임신정황.결과 관찰조치료후분강증상개선솔위87.1％、임신솔위79.3％,고우대조조적70.7％、52.4％(x2 =7.517,4.059,균P＜0.05),관찰조복발솔위19.4％,저우대조조적34.8％(x2=5.581,P＜0.05).결론 복강경술후연합사용GnRH-α치료자궁내막이위증가유효개선환자적분강증상、감소복발화제고임신솔.
Objective To study the clinical effect of GnRH-α in treatment of patients with endometriosis after laparoscope surgery.Methods 185 endometriosis patients who got laparoscope surgery were randomly divided into the observation group(93 cases) and the control group(92 cases),and took GnRH-α and gastrinone,respectively.After 24 months follow-up,the outcomes of pelvic cavity symptom improvement,recurrence and pregnancy were observed.Results After treatment,the pelvic cavity symptom improvement (87.1％ ) and pregnancy rate (79.3 ％ ) in the observation group was higher than those of the control group(70.7％,52.4％ ) (x2 =7.517,4.059,all P ＜0.05),and the recurrence rate( 19.4％ ) in the observation group was lower than that of the control group(34.8％ )(x2 =5.581,P ＜0.05).Conclusion The treatment of endometriosis with GnRH-α combined with laparoscope surgery could attain desirable effect.Compared with gastrinone,it could effectively improve pelvic cavity symptom,decrease recurrence and increase the rate of pregnancy.
