CAJ | 학술논문

目的探讨眼科显微手术后眼前节毒性综合征(toxic anterior segment syndrome,TASS)发生的原因.方法报道2008年10月至2010年4月发生TASS 4例,进行回顾性分析,随诊12月至2年.探讨术后TASS的形成原因.结果 4例TASS病例出现在4例不同的眼科显微手术患者.术后分析,1例患者可能是术后球结膜下注射的庆大霉素误入眼内导致.1例患者可能是视网膜镜经戊二醛熏蒸后,未冲洗干净引起.另2例无明显的致病因素.4例保守治疗效果欠佳,2例最终形成大泡性角膜病变.结论 TASS是眼内显微手术比较少见的并发症,发生原因主要与眼科手术器械残留的消毒药物、术中眼前房内使用的药物、前房内灌注及术后眼局部用药等有关.TASS保守治疗效果欠佳,预防是关键.
목적 탐토안과현미수술후안전절독성종합정(toxic anterior segment syndrome,TASS)발생적원인.방법 보도2008년10월지2010년4월발생TASS 4례,진행회고성분석,수진12월지2년.탐토술후TASS적형성원인.결과 4례TASS병례출현재4례불동적안과현미수술환자.술후분석,1례환자가능시술후구결막하주사적경대매소오입안내도치.1례환자가능시시망막경경무이철훈증후,미충세간정인기.령2례무명현적치병인소.4례보수치료효과흠가,2례최종형성대포성각막병변.결론 TASS시안내현미수술비교소견적병발증,발생원인주요여안과수술기계잔류적소독약물、술중안전방내사용적약물、전방내관주급술후안국부용약등유관.TASS보수치료효과흠가,예방시관건.
Objective To study the causes of toxic anterior segment syndrome (TASS) following eye microsurgery.Methods Four cases of TASS after eye microsurgery in our hospital were analyzed retrospectively between October 1,2008 and April 30,2010.Results Four cases of TASS developed following 4 different Eye Microsurgery,1 case of TASS after trabeculectomy might indicate that the postoperative subconjunctial medications (Gentamycin solution) gained access to the eye,1 case of TASS after vitrectomy might be related to unclean retinascope sterilized by Glutaraldehyde.Specific causes had not been identified in 2 cases of TASS,4 cases of TASS could not be controlled by medical therapy effectively.Two patients developed bullous keratopathy after surgery.Conclusions TASS is a rare complication following uneventful eye microsurgery.The possible causes of TASS include residual preservatives sterilized reusable ocular instruments,intraocular medications,intraocular solutions with inappropriate chemical composition and postoperative extraocular medications.TASS can not be controlled by medical therapy effectively.Prevention of TASS requires careful attention in eye microsurgery.