中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2009年
5期
12-14
,共3页
董平栓%李志娟%邢适颍%王红雷%李道麟%李治国%闫鹏%杨旭明%杨喜山%王绍欣%尚喜燕%李转珍%范喜梅
董平栓%李誌娟%邢適潁%王紅雷%李道麟%李治國%閆鵬%楊旭明%楊喜山%王紹訢%尚喜燕%李轉珍%範喜梅
동평전%리지연%형괄영%왕홍뢰%리도린%리치국%염붕%양욱명%양희산%왕소흔%상희연%리전진%범희매
经皮冠状动脉介入治疗%心肌梗死%左室功能%超声心动图
經皮冠狀動脈介入治療%心肌梗死%左室功能%超聲心動圖
경피관상동맥개입치료%심기경사%좌실공능%초성심동도
Percutaneous coronary intervention%Acute myocardial infarction%Left ventricular function%Echocardiography
目的 观察急诊经皮冠状动脉介入治疗(PCI)对老年急性心肌梗死(AMI)患者的临床疗效及对恢复期左室重构的影响.方法 将128例老年AMI患者随机分为2组,其中急诊PCI组66例,对照组62例,PCI组于发病12 h内行急诊PCI术.对照组给于尿激酶150万单位静脉溶栓治疗.两组患者均给予抗凝、抗血小板药物及其他冠心病二级预防药物治疗.观察住院期间及1年内的心血管不良事件(MACE),并分别于发病后1、6个月做心脏彩超了解心功能及左室重构情况.结果 与对照组相比,急诊PCI组住院期间及1年内MACE发生率明显降低(P＜0.01);两组患者在发病1个月后左心室容积及射血分数差异无统计学意义,发病6个月后,PCI组左心室容积小于对照组(P＜0.05),射血分数高于对照组(P＜0.05),差异有统计学意义.结论 急诊PCI可减少老年AMI患者MACE发生率,能阻止患者左室重构,改善其远期左室功能.
目的 觀察急診經皮冠狀動脈介入治療(PCI)對老年急性心肌梗死(AMI)患者的臨床療效及對恢複期左室重構的影響.方法 將128例老年AMI患者隨機分為2組,其中急診PCI組66例,對照組62例,PCI組于髮病12 h內行急診PCI術.對照組給于尿激酶150萬單位靜脈溶栓治療.兩組患者均給予抗凝、抗血小闆藥物及其他冠心病二級預防藥物治療.觀察住院期間及1年內的心血管不良事件(MACE),併分彆于髮病後1、6箇月做心髒綵超瞭解心功能及左室重構情況.結果 與對照組相比,急診PCI組住院期間及1年內MACE髮生率明顯降低(P＜0.01);兩組患者在髮病1箇月後左心室容積及射血分數差異無統計學意義,髮病6箇月後,PCI組左心室容積小于對照組(P＜0.05),射血分數高于對照組(P＜0.05),差異有統計學意義.結論 急診PCI可減少老年AMI患者MACE髮生率,能阻止患者左室重構,改善其遠期左室功能.
목적 관찰급진경피관상동맥개입치료(PCI)대노년급성심기경사(AMI)환자적림상료효급대회복기좌실중구적영향.방법 장128례노년AMI환자수궤분위2조,기중급진PCI조66례,대조조62례,PCI조우발병12 h내행급진PCI술.대조조급우뇨격매150만단위정맥용전치료.량조환자균급여항응、항혈소판약물급기타관심병이급예방약물치료.관찰주원기간급1년내적심혈관불량사건(MACE),병분별우발병후1、6개월주심장채초료해심공능급좌실중구정황.결과 여대조조상비,급진PCI조주원기간급1년내MACE발생솔명현강저(P＜0.01);량조환자재발병1개월후좌심실용적급사혈분수차이무통계학의의,발병6개월후,PCI조좌심실용적소우대조조(P＜0.05),사혈분수고우대조조(P＜0.05),차이유통계학의의.결론 급진PCI가감소노년AMI환자MACE발생솔,능조지환자좌실중구,개선기원기좌실공능.
Objective To oblige the impact of primary percutaneous coronary intervention(PCI)on the efficacy and left ventricular(LV)remodeling in elderly acute myocardial infarction(AMI)patients.Methods 128 cases of elderly patients with AMI were randomly divided into two groups,66 patients in PCI group and 62 in control group.The individuals in PCI group were performed PCI within 12 hours after onset of AMI.The individuals in the control group were injected into 1.5 million units Urokinase to dissolve thrombus.Two groups of patients took long-term anticoagulant,anti-platelet drugs and secondary prevention of coronary heart disease drugs.After one month and six months,the observation the major adverse cardiac events(MACE)at one year were studied and echocardiography examinations were performed to assess the channel in LV volumes,systolic function of all the individuals.Results In PCI group,the occurrence of MACE at one year were lower than those in control group(P＜0.01).The LV volumeand systolic function were no difference between the two groups after one month(P＜0.05).The LV volume was decreased(P＜0.05)and systolic function was improved(P＜0.05)after six months.Condusions Primary PCI of elderly patients with AMI Can reduce che occasion of MACE and sinnificantly prevent the left ventricle reconstitution and improve the left ventricle prognosis in long-term.
