国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2009年
1期
23-25
,共3页
汪隆海%张平%陈启松
汪隆海%張平%陳啟鬆
왕륭해%장평%진계송
利钠肽,脑%心力衰竭,充血性%诊断
利鈉肽,腦%心力衰竭,充血性%診斷
리납태,뇌%심력쇠갈,충혈성%진단
Natriuretic peptide，brain%Heart failure，congestive%Diagnosis
目的 评价血清N末端脑钠肽(NT-proBNP)定量检测对心力衰竭患者的诊断价值.方法 采用定量ELISA改进法检测不同心衰程度的患者血清NT-proBNP.结果 心衰患者血清NT-proBNP水平明显增高,并随心衰患者程度加重呈指数增加;实验受试者工作特征曲线下面积为0.898;心衰的诊断敏感性和特异性分别为91.9%和92.3%.结论 定量检测血清NT-proBNP是目前用于评价心衰患者的最佳实验手段.
目的 評價血清N末耑腦鈉肽(NT-proBNP)定量檢測對心力衰竭患者的診斷價值.方法 採用定量ELISA改進法檢測不同心衰程度的患者血清NT-proBNP.結果 心衰患者血清NT-proBNP水平明顯增高,併隨心衰患者程度加重呈指數增加;實驗受試者工作特徵麯線下麵積為0.898;心衰的診斷敏感性和特異性分彆為91.9%和92.3%.結論 定量檢測血清NT-proBNP是目前用于評價心衰患者的最佳實驗手段.
목적 평개혈청N말단뇌납태(NT-proBNP)정량검측대심력쇠갈환자적진단개치.방법 채용정량ELISA개진법검측불동심쇠정도적환자혈청NT-proBNP.결과 심쇠환자혈청NT-proBNP수평명현증고,병수심쇠환자정도가중정지수증가;실험수시자공작특정곡선하면적위0.898;심쇠적진단민감성화특이성분별위91.9%화92.3%.결론 정량검측혈청NT-proBNP시목전용우평개심쇠환자적최가실험수단.
Objective To evaluate the diagnostic value of N-terminal pro-brain natriuretic peptide (NT-proBNP) quantitative detection in patients with heart failure.Methods Quantitative enzyme-linked immunosorbent assay (ELISA) improvement method was applied to measuring serum level of NT-proBNP in patients with different degree of heart failure.Results The serum level of NT-proBNP was significantly elevated in patients with heart failure. With the increase of extent of heart failure, NT-proBNP increased in exponent. Receiver operator characteristic curve (ROC) showed that area under curve (AUC) was 0.898. The sensitivity and specificity were 91.9% and 92.3% respectively for diagnosis of heart failure.Conclusion Quantitative detection of NT-proBNP is at present the best laboratory test for evaluating heart function of patients with heart failure.
