CAJ | 학술논문

目的探讨纤维支气管镜治疗慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)合并呼吸衰竭的临床疗效.方法将60例COPD合并呼吸衰竭的患者随机分为治疗组和对照组,每组30例;对照组常规抗感染、祛痰、吸氧等对症治疗,治疗组在此基础上通过纤维支气管镜吸痰、支气管肺泡灌洗;治疗2周后观察两组的临床疗效.结果治疗组中好转28例,有效率93.3%;对照组中好转21例,有效率70.0%,治疗组有效率高于对照组(P＜0.05);临床症状、血气分析和肺功能改善明显,对照组比较差异有统计学意义(P＜0.01).结论经纤维支气管镜治疗COPD合并呼吸衰竭患者疗效确切、安全,减轻症状,减少气管插管率,促进患者康复,具有重要的临床应用价值.
목적 탐토섬유지기관경치료만성조새성폐질병(chronic obstructive pulmonary disease,COPD)합병호흡쇠갈적림상료효.방법 장60례COPD합병호흡쇠갈적환자수궤분위치료조화대조조,매조30례;대조조상규항감염、거담、흡양등대증치료,치료조재차기출상통과섬유지기관경흡담、지기관폐포관세;치료2주후관찰량조적림상료효.결과 치료조중호전28례,유효솔93.3%;대조조중호전21례,유효솔70.0%,치료조유효솔고우대조조(P＜0.05);림상증상、혈기분석화폐공능개선명현,대조조비교차이유통계학의의(P＜0.01).결론 경섬유지기관경치료COPD합병호흡쇠갈환자료효학절、안전,감경증상,감소기관삽관솔,촉진환자강복,구유중요적림상응용개치.
Objective To evaluate the efficacy of fiberbronchoscope in chronic obstructive pulmonary disease (COPD) patients with respiratory failure. Methods 30 patients with COPD were included in the study group after randomization, and 30 patients served as control group. The control group was treated by conventional anti-infective, expectorant, oxygen and other symptomatic treatment.The study group were added on the basis of suction and bronchoalveolar lavage through the bronchoscope.Clinical efficacy were observed after 2 weeks of treatment. Results Its improvement rate and clinical efficiency have been increased in study group than those of control group ( P ＜0. 05). Compared with the results of control group,study group improved significantly in clinical symptoms, blood gas indexes and pulmonary function ( P ＜ 0. 01). Conclusions The results suggest that fiberbronchoscope can offer confirmed efficiency and safety treatment in COPD patients with respiratory failure, and can alleviate symptoms,decrease endotracheal intubation rate and promote recovery, with important clinical value.