CAJ | 학술논문

目的评价小牛血去蛋白提取物眼用凝胶治疗LASIK术后干眼症的临床治疗效果.方法取2008年1月至2009年12月间在行LASIK手术后发生干眼症的单纯近视及近视散光患者76例(152只眼),采用自身对照法,每例随机选取一只眼进入治疗组(小牛血去蛋白提取物眼用凝胶滴眼)；另一只眼进入对照组(0.1％玻璃酸钠滴眼液滴眼).术后1d、1周、1月、3月观察眼部不适主诉、Shirmer Ⅰ试验、BUT、荧光素染色结果.结果眼部不适主诉术后1周、1月实验组明显低于对照组(P ＜0.05)；ShirmerⅠ试验术后1周、1月实验组明显长于对照组(P＜0.05)；BUT术后1周、1月、3月实验组明显长于对照组(P＜0.05)；荧光素染色分级术后1d和1月实验组明显低于对照组(P＜0.05).结论小牛血去蛋白提取物眼用凝胶治疗LASIK术后干眼症疗效确切、起效时间短、能够有效改善患者不适症状及体征.
목적 평개소우혈거단백제취물안용응효치료LASIK술후간안증적림상치료효과.방법 취2008년1월지2009년12월간재행LASIK수술후발생간안증적단순근시급근시산광환자76례(152지안),채용자신대조법,매례수궤선취일지안진입치료조(소우혈거단백제취물안용응효적안)；령일지안진입대조조(0.1％파리산납적안액적안).술후1d、1주、1월、3월관찰안부불괄주소、Shirmer Ⅰ시험、BUT、형광소염색결과.결과 안부불괄주소술후1주、1월실험조명현저우대조조(P ＜0.05)；ShirmerⅠ시험술후1주、1월실험조명현장우대조조(P＜0.05)；BUT술후1주、1월、3월실험조명현장우대조조(P＜0.05)；형광소염색분급술후1d화1월실험조명현저우대조조(P＜0.05).결론 소우혈거단백제취물안용응효치료LASIK술후간안증료효학절、기효시간단、능구유효개선환자불괄증상급체정.
Objective To evaluate the treatment effect of expression of protein-free calf blood extract gel in dry eyes after LASIK.Methods A total of 76 cases (152 eyes) of dry eye after LASIK were collected for study.Each case was chosen one eye into experiment group (treated with protein-free calf blood extract gel) and the other eye into control group (treated by 0.1％ sodium hyaluronate drop) at random.The discomfortness of eyes,Shirmer Ⅰ test,tear breaking-up time (BUT)and fluorescent bangle staining of cornea were tested and marked after 1 day,1 week,1 month and 3months after LASIK.Results Between experiment group and control group,the discomfortness of eyes were significant less in experiment group at 1 week and 1 month after LASIK (P ＜0.05); the Shirmer Ⅰ test wetting were significant length at 1 week and 1 month after LASIK (P ＜0.05); the BUT were significant longer at 1 week,1 month and 3 months after LASIK (P ＜0.05); the level of fluorescent bangle staining of cornea were significant reduced at 1 day and 1 month after LASIK (P＜0.05).Conclusions Protein-free calf blood extract gel can be used to improve on the symptom,objective sign in dry eyes after LASIK.