中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2012年
24期
9-11
,共3页
休克,出血性%急救医疗服务%羟乙基淀粉
休剋,齣血性%急救醫療服務%羥乙基澱粉
휴극,출혈성%급구의료복무%간을기정분
Shock,hemorrhagic%Emergency medical services%Hetastarch
目的 探讨羟乙基淀粉130/0.4氯化钠注射液复苏方法对早期失血性休克的临床疗效.方法 将52例早期失血性休克患者按随机数字表法分为复方氯化钠注射液组(对照组)和羟乙基淀粉130/0.4氯化钠注射液组(治疗组),每组26例,观察比较两组患者治疗效果,治疗前和治疗后60 min的平均动脉压、呼吸频率和心率以及血钠、血氯和凝血酶原时间.结果 治疗组和对照组治愈率分别为84.6％(22/26)和38.5％(10/26),病死率分别为15.4％(4/26)和61.5％(16/26),两组比较差异均有统计学意义(P＜0.05).治疗组治疗后60 min平均动脉压、心率和呼吸频率均较对照组明显改善[(91.5±8.6) mm Hg(1 mm Hg =0.133 kPa)比(78.5±7.9) mm Hg、(81.5±8.6)次/min比(108.4±10.2)次/min、(21.4±5.3)次/min比(25.5±4.6)次/min,P＜0.05]；两组治疗前与治疗后60min血钠、血氯、凝血酶原时间比较差异无统计学意义(P＞0.05).结论 采用羟乙基淀粉130/0.4氯化钠注射液复苏方法治疗早期失血性休克可增加有效循环血量,改善组织器官灌注,降低病死率.
目的 探討羥乙基澱粉130/0.4氯化鈉註射液複囌方法對早期失血性休剋的臨床療效.方法 將52例早期失血性休剋患者按隨機數字錶法分為複方氯化鈉註射液組(對照組)和羥乙基澱粉130/0.4氯化鈉註射液組(治療組),每組26例,觀察比較兩組患者治療效果,治療前和治療後60 min的平均動脈壓、呼吸頻率和心率以及血鈉、血氯和凝血酶原時間.結果 治療組和對照組治愈率分彆為84.6％(22/26)和38.5％(10/26),病死率分彆為15.4％(4/26)和61.5％(16/26),兩組比較差異均有統計學意義(P＜0.05).治療組治療後60 min平均動脈壓、心率和呼吸頻率均較對照組明顯改善[(91.5±8.6) mm Hg(1 mm Hg =0.133 kPa)比(78.5±7.9) mm Hg、(81.5±8.6)次/min比(108.4±10.2)次/min、(21.4±5.3)次/min比(25.5±4.6)次/min,P＜0.05]；兩組治療前與治療後60min血鈉、血氯、凝血酶原時間比較差異無統計學意義(P＞0.05).結論 採用羥乙基澱粉130/0.4氯化鈉註射液複囌方法治療早期失血性休剋可增加有效循環血量,改善組織器官灌註,降低病死率.
목적 탐토간을기정분130/0.4록화납주사액복소방법대조기실혈성휴극적림상료효.방법 장52례조기실혈성휴극환자안수궤수자표법분위복방록화납주사액조(대조조)화간을기정분130/0.4록화납주사액조(치료조),매조26례,관찰비교량조환자치료효과,치료전화치료후60 min적평균동맥압、호흡빈솔화심솔이급혈납、혈록화응혈매원시간.결과 치료조화대조조치유솔분별위84.6％(22/26)화38.5％(10/26),병사솔분별위15.4％(4/26)화61.5％(16/26),량조비교차이균유통계학의의(P＜0.05).치료조치료후60 min평균동맥압、심솔화호흡빈솔균교대조조명현개선[(91.5±8.6) mm Hg(1 mm Hg =0.133 kPa)비(78.5±7.9) mm Hg、(81.5±8.6)차/min비(108.4±10.2)차/min、(21.4±5.3)차/min비(25.5±4.6)차/min,P＜0.05]；량조치료전여치료후60min혈납、혈록、응혈매원시간비교차이무통계학의의(P＞0.05).결론 채용간을기정분130/0.4록화납주사액복소방법치료조기실혈성휴극가증가유효순배혈량,개선조직기관관주,강저병사솔.
Objective To investigate the clinical efficacy of hydroxyethyl starch 130/0.4 and sodium chloride injection in the treatment of patients with early hemorrhagic shock (HS).Methods Fifty-two cases of early HS were divided into compound sodium chloride injection group (control group,26 cases) and hydroxyethyl starch 130/0.4 sodium chloride injection group (treatment group,26 cases) by random digits table.The clinical effect,mean arterial pressure (MAP),respiratory rate (RR) and heart rate (HR) and serum sodium,serum chloride and prothrombin time (PT) were statistically analyzed before and after treatment for 60 min.Results Cure rates in treatment group and control group were 84.6％ (22/26) and 38.5％ (10/26),and mortality rates were 15.4％ (4/26) and 61.5％ (16/26),respectively.The difference showed statistical significant (P ＜0.05).MAP,HR and RR in treatment group were obviously improved compared with control group[ (91.5 ± 8.6 )mm Hg( 1 mm Hg =0.133 kPa) vs.(78.5 ± 7.9 )mm H8,( 81.5 ±8.6) times/min vs.( 108.4 ± 10.2) times/min,(21.4 ± 5.3) times/min vs.(25.5 ± 4.6) times/min,P ＜ 0.05 ].Compared with control group,serum sodium,serum chloride and PT in treatment group were no significant difference (P ＞0.05).Conclusion Hydroxyethyl starch 130/0.4 and sodium chloride injection could increase the effective circulating blood volume,and improve tissue and organ perfusion and reduce mortality during the patients with early HS.
