CAJ | 학술논문

苯并噻唑及其衍生物由于其独特的抗感染和抗肿瘤的特性,近年来引起广泛关注.本文报导了一种新的合成苯并噻唑类衍生物的方法:硫代苯甲酸乙酯与邻氨基疏基取代苯的缩合.这种方法操作简便,反应条件温和.尤其适合于底物有活泼官能团的情况.应用此方法,高收率合成了六个化合物.
분병새서급기연생물유우기독특적항감염화항종류적특성,근년래인기엄범관주.본문보도료일충신적합성분병새서류연생물적방법:류대분갑산을지여린안기소기취대분적축합.저충방법조작간편,반응조건온화.우기괄합우저물유활발관능단적정황.응용차방법,고수솔합성료륙개화합물.
Benzothiazole derivatives have been drawing great attention due to their antimalarial and antitumor properties. We reported a new approach to prepare benzothiazoles: condensation of thioethylbenzoate with 2-aminothiophenols. The operation is convenient and the reaction proceeds in mild condition. Six compounds in good yields were synthesized by this method.